Anti-NMO (Neuromyelitis Optica) Antibody / Aquaporin 4 Test
Short Name: Anti-NMO Antibody Test
Also known as: Aquaporin 4 Antibody Test, NMO Antibody Test, Devic's Disease Antibody Test, Anti-Aquaporin 4 Test
Anti-NMO (Neuromyelitis Optica) Antibody / Aquaporin 4 Test test available at DNA Labs India for ₹6,500. Uses Immunofluorescence Assay on Serum or Cerebrospinal Fluid (CSF) samples. Results in Same day report if sample is received by 9 am on Tuesday or Friday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Anti-NMO Antibody Test is to detect the presence of Aquaporin 4 antibodies, which are biomarkers for Neuromyelitis Optica. It aids in confirming diagnosis, differentiating NMO from other neurological disorders like Multiple Sclerosis, and guiding treatment decisions.
- Test Code
- 158
- Price
- ₹6,500
- Sample Type
- Serum or Cerebrospinal Fluid (CSF)
- Result Time
- Same day report if sample is received by 9 am on Tuesday or Friday.
- Fasting Required
- No
- Method
- Immunofluorescence Assay
Sample Collection
No special preparation such as fasting is required. Inform your doctor about any medications or health conditions.
Method: Venipuncture for blood draw; lumbar puncture for CSF
Laboratory Analysis
For blood sample, a needle is inserted into a vein to collect serum. For CSF, a lumbar puncture is performed by a healthcare professional.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Mild discomfort may occur, but serious risks are rare.
Timeline: Same day report if sample is received by 9 am on Tuesday or Friday.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Anti-NMO Antibody Test is to detect the presence of Aquaporin 4 antibodies, which are biomarkers for Neuromyelitis Optica. It aids in confirming diagnosis, differentiating NMO from other neurological disorders like Multiple Sclerosis, and guiding treatment decisions.
How to Prepare
- Serum: Collect 2 mL blood in an SST tube, centrifuge, and ship refrigerated or frozen.
- CSF: Collect 1 mL in a sterile screw-capped container and ship refrigerated or frozen.
- Label samples properly with patient details.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for diagnosing Neuromyelitis Optica, especially when symptoms mimic other neurological conditions like Multiple Sclerosis. Early detection helps in targeted treatment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
Understanding Your Results
Positive
Indicates the presence of Aquaporin 4 antibodies, consistent with Neuromyelitis Optica. Clinical correlation is necessary.
Negative
No detectable antibodies. NMO is less likely, but other conditions should be considered if symptoms persist.
Consult a doctor immediately if you experience sudden vision loss, severe eye pain, limb weakness, numbness, or bladder/bowel issues. If the test result is positive, follow up with a neurologist or immunologist for management.
Limitations
- ⚠False negatives can occur in early stages or with low antibody titers.
- ⚠Results should be interpreted in conjunction with clinical findings and other tests.
Risks & Considerations
- ●For blood draw: minor bruising, pain, or infection at the puncture site.
- ●For lumbar puncture: headache, back pain, or, rarely, infection or bleeding.
Frequently Asked Questions
What is the cost of the Anti-NMO Antibody Test in India?
What are the symptoms of Neuromyelitis Optica (NMO)?
How is NMO diagnosed?
What sample is required for the test?
Is fasting required before the test?
How long does it take to get the test reports?
Is home sample collection available for this test?
What does a positive test result mean?
Can this test be done during pregnancy?
What are the risks associated with the test?
How accurate is the Anti-NMO Antibody Test?
Who should consider taking this test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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