ANCA-PR3 (Serine Proteinase 3 Antibodies) EIA Test
Short Name: ANCA-PR3 EIA
Also known as: Anti-PR3 Antibodies Test, c-ANCA Test, Serine Proteinase 3 Antibodies EIA
ANCA-PR3 (Serine Proteinase 3 Antibodies) EIA Test test available at DNA Labs India for ₹2,106. Uses Enzyme Immunoassay on Serum samples. Results in Reports are available on the same day as sample collection, with digital delivery options.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The ANCA-PR3 EIA test detects antibodies against Serine Proteinase 3 (PR3), which are biomarkers for autoimmune vasculitis, especially granulomatosis with polyangiitis (GPA). It aids in diagnosis, monitoring disease activity, and guiding treatment decisions.
- Test Code
- 120
- Price
- ₹2,106
- Sample Type
- Serum
- Result Time
- Reports are available on the same day as sample collection, with digital delivery options.
- Fasting Required
- No
- Method
- Enzyme Immunoassay
Sample Collection
No special preparation required. Inform your healthcare provider about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will draw a blood sample from a vein in your arm using a sterile needle and syringe.
Report Delivery
Apply gentle pressure to the puncture site with a cotton ball to stop bleeding. Avoid heavy lifting or strenuous activity for a few hours.
Timeline: Reports are available on the same day as sample collection, with digital delivery options.
Patient Instructions
About This Test
Who Should Get This Test
The ANCA-PR3 EIA test detects antibodies against Serine Proteinase 3 (PR3), which are biomarkers for autoimmune vasculitis, especially granulomatosis with polyangiitis (GPA). It aids in diagnosis, monitoring disease activity, and guiding treatment decisions.
How to Prepare
- Use a sterile needle and syringe for venipuncture
- Collect 2 mL of blood in an SST tube
- Label the tube with patient details and date
- Store the sample appropriately before transport
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"The ANCA-PR3 EIA test is crucial for detecting antibodies associated with granulomatosis with polyangiitis and other vasculitides. Early diagnosis enables timely treatment and better patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume (<1 mL)
- Incorrect sample type (not serum)
- Improper storage or stability issues
- Clotted or hemolyzed samples
Understanding Your Results
Positive
Suggests the presence of autoimmune vasculitis, such as granulomatosis with polyangiitis. Further evaluation is recommended.
Negative
PR3 antibodies not detected; vasculitis is less likely, but clinical symptoms should be monitored.
Consult a healthcare provider if you experience symptoms like persistent fever, weight loss, joint pain, or respiratory issues, especially if they worsen or do not resolve.
Limitations
- ⚠Cannot distinguish between active and past disease
- ⚠May be negative in some vasculitis subtypes
- ⚠Not a standalone diagnostic; requires clinical correlation
Risks & Considerations
- ●Minor bruising or hematoma at the puncture site
- ●Rare risk of infection
- ●Temporary dizziness or lightheadedness
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Recent infections or vaccinations
- ●Certain medications like immunosuppressants
Compare With Similar Tests
| Test | ANCA-PR3 (Serine Proteinase 3 Antibodies) EIA Test | ANCA-MPO EIA | C-Reactive Protein (CRP) | Erythrocyte Sedimentation Rate (ESR) | Tissue Biopsy |
|---|---|---|---|---|---|
| Comparison | ANCA-PR3 (Serine Proteinase 3 Antibodies) EIA Test |
Frequently Asked Questions
What is the ANCA-PR3 EIA test?
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