Anti Neutrophil Cytoplasmic Antibody (ANCA) Panel Serum Test
Short Name: ANCA Panel Serum Test
Also known as: ANCA Test, ANCA Serum Test, Anti-Neutrophil Cytoplasmic Antibody Test
Anti Neutrophil Cytoplasmic Antibody (ANCA) Panel Serum Test test available at DNA Labs India for ₹6,500. Uses Immunofluorescence Assay (IFA), Enzyme Immunoassay (ELISA) on Serum samples. Results in Same day report if sample collected by 9 AM on Tuesday, Thursday, or Saturday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The ANCA Panel Serum Test is performed to diagnose autoimmune vasculitis and other related disorders. It includes ANCA by immunofluorescence assay (IFA) to detect antibody patterns, and enzyme immunoassay (ELISA) for specific antigens: ANCA-MPO (myeloperoxidase) and ANCA-PR3 (proteinase 3). This helps in identifying conditions like granulomatosis with polyangiitis and microscopic polyangiitis, and monitors treatment efficacy.
- Test Code
- 142
- Price
- ₹6,500
- Sample Type
- Serum
- Result Time
- Same day report if sample collected by 9 AM on Tuesday, Thursday, or Saturday.
- Fasting Required
- Yes (8 hours)
- Method
- Immunofluorescence Assay (IFA), Enzyme Immunoassay (ELISA)
Sample Collection
Overnight fasting is preferred. Inform your doctor about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm using standard venipuncture technique.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities unless advised otherwise.
Timeline: Same day report if sample collected by 9 AM on Tuesday, Thursday, or Saturday.
Patient Instructions
About This Test
Who Should Get This Test
The ANCA Panel Serum Test is performed to diagnose autoimmune vasculitis and other related disorders. It includes ANCA by immunofluorescence assay (IFA) to detect antibody patterns, and enzyme immunoassay (ELISA) for specific antigens: ANCA-MPO (myeloperoxidase) and ANCA-PR3 (proteinase 3). This helps in identifying conditions like granulomatosis with polyangiitis and microscopic polyangiitis, and monitors treatment efficacy.
How to Prepare
- Collect 3 mL (2 mL min.) serum from one SST
- Ship refrigerated or frozen
- Ensure sample is labeled correctly
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"The ANCA panel is crucial for diagnosing vasculitis and other autoimmune conditions. Early detection can lead to better management and improved patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or lipemic samples
- Insufficient sample volume
- Improper storage or labeling
Understanding Your Results
Negative ANCA by IFA and normal MPO/PR3 levels
No evidence of ANCA-associated vasculitis
Positive ANCA by IFA with elevated MPO antibodies
May indicate microscopic polyangiitis or other vasculitis
Positive ANCA by IFA with elevated PR3 antibodies
May suggest granulomatosis with polyangiitis
Consult your doctor if you have symptoms of autoimmune disorders or if test results are positive. Seek immediate care for severe symptoms like shortness of breath or blood in urine.
Limitations
- ⚠False positives can occur in infections or other autoimmune conditions
- ⚠Results must be correlated with clinical symptoms
- ⚠Does not replace comprehensive clinical evaluation
Risks & Considerations
- ●Minor bruising or soreness at the puncture site
- ●Rare risk of infection or dizziness
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Certain medications like immunosuppressants
- ●Recent infections or vaccinations
- ●Sample storage issues
Compare With Similar Tests
| Test | Anti Neutrophil Cytoplasmic Antibody (ANCA) Panel Serum Test | |||
|---|---|---|---|---|
| Comparison | Anti Neutrophil Cytoplasmic Antibody (ANCA) Panel Serum Test | Detects nuclear antibodies; broader screening for autoimmune diseases | Specific to rheumatoid arthritis; not specific to vasculitis | Inflammatory markers; non-specific for ANCA disorders |
Frequently Asked Questions
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