C3 & C4 Complement Panel Test
Short Name: C3 & C4 Complement Panel
Also known as: Complement C3 and C4 Test, Complement Panel Test, C3 C4 Blood Test
C3 & C4 Complement Panel Test test available at DNA Labs India for ₹1,463. Uses Immunoturbidimetry on Serum samples. Results in Reports are available within 24 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To assess the levels of complement proteins C3 and C4 in the blood, which are essential for immune function. This test helps in diagnosing autoimmune diseases, monitoring disease activity, and evaluating response to treatment.
- Test Code
- 236
- Price
- ₹1,463
- Sample Type
- Serum
- Result Time
- Reports are available within 24 hours.
- Fasting Required
- Yes (8 hours)
- Method
- Immunoturbidimetry
Sample Collection
Overnight fasting for 8-12 hours is preferred. Stay hydrated and inform your doctor about any medications.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Avoid heavy lifting for a few hours.
Timeline: Reports are available within 24 hours.
Patient Instructions
About This Test
Who Should Get This Test
To assess the levels of complement proteins C3 and C4 in the blood, which are essential for immune function. This test helps in diagnosing autoimmune diseases, monitoring disease activity, and evaluating response to treatment.
How to Prepare
- Fast overnight for 8-12 hours before the test
- Drink plenty of water
- Wear loose clothing for easy access to arm
- Inform the phlebotomist about any medications or supplements
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"C3 and C4 complement levels are key markers for diagnosing autoimmune and immune complex diseases. This test aids in early detection and management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Incorrect sample type
- Contaminated sample
Understanding Your Results
May indicate active autoimmune diseases like lupus, rheumatoid arthritis, or immune complex diseases.
Level: Low C3 and C4
Can be seen in acute inflammation, infection, or as a response to tissue damage.
Level: High C3 and C4
Suggest no significant complement consumption or deficiency, but clinical correlation is needed.
Level: Normal levels
If test results are abnormal or if you experience symptoms like persistent fatigue, joint pain, or frequent infections, consult an immunologist or rheumatologist for further evaluation.
Limitations
- ⚠May not detect all immune disorders
- ⚠Results should be interpreted in clinical context
- ⚠False positives/negatives possible
Risks & Considerations
- ●Minor bruising at the puncture site
- ●Rare chance of infection
- ●Slight pain during blood draw
Interfering Factors
- ●Medications such as corticosteroids
- ●Acute phase reactions
- ●Liver disease
- ●Genetic deficiencies
Frequently Asked Questions
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