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Anti IA-2 (Insulinoma Associated Antigen) Test

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Anti IA-2 (Insulinoma Associated Antigen) Test

Short Name: Anti IA-2 Test

Also known as: IA-2 Antibody Test, Insulinoma Associated Antigen Test

Anti IA-2 (Insulinoma Associated Antigen) Test test available at DNA Labs India for ₹7,500. Uses Enzyme Immunoassay on Serum samples. Results in Results are typically available within 24 hours after sample collection.. Free home collection in 300+ cities across India.

Blood TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect antibodies against IA-2 antigen for diagnosing insulinoma and assessing related endocrine disorders.

Test Code
140
Price
₹7,500
Sample Type
Serum
Result Time
Results are typically available within 24 hours after sample collection.
Fasting Required
No
Method
Enzyme Immunoassay
Step 1

Sample Collection

No special preparation required. Inform your doctor about any medications or supplements you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is drawn from a vein in your arm using a sterile needle. The process takes a few minutes and may cause mild discomfort.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Avoid heavy lifting or strenuous activity for a few hours.

Timeline: Results are typically available within 24 hours after sample collection.

Patient Instructions

1
Before the Test:No fasting or special preparation needed. Ensure you are hydrated and inform the technician of any allergies.
2
During the Test:A phlebotomist will clean the area, insert a needle to draw blood, and apply a bandage after collection.
3
After the Test:You can resume normal activities immediately. Monitor the puncture site for any signs of bruising or infection.

About This Test

Who Should Get This Test

To detect antibodies against IA-2 antigen for diagnosing insulinoma and assessing related endocrine disorders.

How to Prepare

  • Ensure the sample is collected in a SST tube.
  • Ship refrigerated or frozen as per stability guidelines.
  • Label the sample correctly with patient details.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is crucial for differentiating insulinoma from other causes of hypoglycemia, ensuring accurate diagnosis and timely treatment."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerator (2-8°C): 2 weeks
Frozen (-20°C): 6 months
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Insufficient sample volume
  • Improper labeling or storage
  • Sample older than stability period

Understanding Your Results

Results indicate the presence or absence of Anti IA-2 antibodies. A positive result may suggest insulinoma or related autoimmune conditions, but clinical correlation is essential.
📊

Negative

No detectable antibodies; insulinoma is less likely, but further tests may be needed based on symptoms.

📊

Positive

Antibodies detected; supports diagnosis of insulinoma. Consult an endocrinologist for confirmatory tests like imaging.

📊

Equivocal

Borderline results; repeat testing or additional evaluation recommended.

⚠️ When to Consult a Doctor:

If you experience recurrent hypoglycemia symptoms or have a positive test result, consult an endocrinologist immediately for further evaluation and management.

Limitations

  • Cannot confirm insulinoma alone; requires correlation with imaging and clinical symptoms
  • May have cross-reactivity with other autoantibodies
  • Not suitable for monitoring treatment response

Risks & Considerations

  • Minor pain or bruising at the puncture site
  • Rare risk of infection or fainting
  • No significant long-term risks

Interfering Factors

  • Recent infections or autoimmune conditions
  • Use of immunosuppressive medications
  • Sample hemolysis or lipemia
  • Improper sample storage or handling

Compare With Similar Tests

TestAnti IA-2 (Insulinoma Associated Antigen) TestInsulin TestC-Peptide TestFasting Glucose TestCT Scan/MRI
ComparisonAnti IA-2 (Insulinoma Associated Antigen) TestMeasures insulin levels directly; often used alongside Anti IA-2 for comprehensive assessment.Evaluates endogenous insulin production; helps distinguish insulinoma from factitious hypoglycemia.Assesses blood sugar levels during fasting; used to detect hypoglycemia patterns.Imaging tests to visualize pancreatic tumors; recommended after positive antibody tests.

Frequently Asked Questions

What is the Anti IA-2 Insulinoma Associated Antigen Test?
It is a blood test that detects antibodies against the IA-2 protein, used to help diagnose insulinoma, a rare pancreatic tumor causing low blood sugar.
What is the cost of this test in India?
The test costs INR 7500 at DNA Labs India, with free home sample collection available across major cities.
Do I need to fast before the test?
No, fasting is not required. No special preparation is needed for this test.
How is the sample collected?
A small blood sample is drawn from a vein in your arm using a sterile needle and collected in a serum separator tube.
When will I get the results?
Results are typically available within 24 hours after sample collection, accessible via online portal, email, or WhatsApp.
What does a positive result mean?
A positive result indicates the presence of Anti IA-2 antibodies, which may support a diagnosis of insulinoma. Consult an endocrinologist for further evaluation.
Is this test covered by insurance?
Coverage varies by insurance provider. It is advisable to check with your insurer before booking the test.
Can this test be done at home?
Yes, DNA Labs India offers free home sample collection for this test in over 200 cities across India.
What are the symptoms of insulinoma?
Symptoms include recurrent hypoglycemia, dizziness, fainting, seizures, confusion, sweating, and irritability.
How accurate is this test?
The test uses Enzyme Immunoassay, which is reliable, but results should be interpreted alongside clinical symptoms and other diagnostic tests.
Are there any risks associated with the test?
The risks are minimal, such as slight pain or bruising at the blood draw site. Serious complications are rare.
What other tests are needed to diagnose insulinoma?
Additional tests may include insulin levels, C-peptide tests, fasting glucose tests, CT scans, or MRI to confirm insulinoma and assess tumor location.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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