Bacterial Genome Sequencing and Reference Based Analysis Test
Short Name: Bacterial Genome Sequencing
Also known as: Bacterial WGS, Reference-based bacterial sequencing, Bacterial genome analysis
Bacterial Genome Sequencing and Reference Based Analysis Test test available at DNA Labs India for ₹24,000. Uses Next-Generation Sequencing (NGS), Reference-based bioinformatics analysis on Extracted DNA samples. Results in Results are typically available within 8 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of bacterial genome sequencing and reference-based analysis is to provide a comprehensive genetic profile of a bacterial pathogen. This includes precise identification of the bacterial species and strain, detection of virulence factors that contribute to pathogenicity, and identification of antibiotic resistance genes that may predict treatment failure. This information aids clinicians in selecting the most effective antibiotics, implementing appropriate infection control measures, and understanding the epidemiology of the infection. Additionally, it can be used for outbreak investigations, molecular typing, and surveillance of emerging resistance patterns.
- Test Code
- 6339
- CPT Code
- N/A
- ICD Code
- N/A
- Price
- ₹24,000
- Sample Type
- Extracted DNA
- Result Time
- Results are typically available within 8 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS), Reference-based bioinformatics analysis
Sample Collection
No special preparation is required. However, if the sample is a bacterial culture, it should be collected in a sterile container and transported to the laboratory as per instructions.
Method: Blood or isolated bacterial culture
Laboratory Analysis
The sample (blood or bacterial culture) will be collected by a trained phlebotomist or laboratory technician. For blood samples, standard venipuncture procedure will be followed.
Report Delivery
No specific aftercare is needed. The sample will be processed in the laboratory, and results will be available in approximately 8 weeks.
Timeline: Results are typically available within 8 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of bacterial genome sequencing and reference-based analysis is to provide a comprehensive genetic profile of a bacterial pathogen. This includes precise identification of the bacterial species and strain, detection of virulence factors that contribute to pathogenicity, and identification of antibiotic resistance genes that may predict treatment failure. This information aids clinicians in selecting the most effective antibiotics, implementing appropriate infection control measures, and understanding the epidemiology of the infection. Additionally, it can be used for outbreak investigations, molecular typing, and surveillance of emerging resistance patterns.
How to Prepare
- Ensure the sample is labeled correctly with patient identification
- If providing a bacterial culture, use a sterile swab or container
- Transport the sample to the laboratory at the earliest to maintain viability
- For blood samples, use an EDTA or citrate tube as instructed
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Bacterial genome sequencing provides critical information for managing complex infections, especially when standard cultures fail or resistance is suspected. This test aids in targeted therapy and infection control."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Insufficient quantity of DNA
- Improperly labeled sample
- Sample not transported under appropriate conditions
Understanding Your Results
Presence of antibiotic resistance genes
Indicates potential resistance to specific antibiotics; alternative therapy may be required.
Presence of virulence genes
Suggests increased pathogenicity; may warrant more aggressive treatment or monitoring.
Specific strain identified
Helps in epidemiological tracking and outbreak management.
No significant variants detected
The bacterium is genetically similar to the reference strain; standard treatment may be effective.
Consult your physician if you have persistent or severe symptoms of a bacterial infection, or if you have been referred for this test. Your doctor will interpret the results and recommend appropriate treatment.
Limitations
- ⚠This test is not a substitute for standard culture and susceptibility testing; it provides genetic information that may not always correlate with phenotypic resistance
- ⚠Results may not be available for slow-growing or unculturable bacteria
- ⚠Interpretation requires specialized bioinformatics expertise
- ⚠Cost may be prohibitive for routine use
Risks & Considerations
- ●Minimal risk of bruising or infection at the blood draw site
- ●No significant risks associated with the test itself
Interfering Factors
- ●Poor quality or degraded DNA can lead to incomplete sequencing
- ●Contamination with host DNA or other bacterial species may affect results
- ●Insufficient bacterial DNA concentration may require additional amplification steps
- ●Reference genome choice may influence variant calling accuracy
Compare With Similar Tests
| Test | Bacterial Genome Sequencing and Reference Based Analysis | Conventional Culture and Sensitivity | PCR-based Assays | Whole Genome Sequencing (WGS) |
|---|---|---|---|---|
| Comparison | Bacterial Genome Sequencing and Reference Based Analysis |
Frequently Asked Questions
What is bacterial genome sequencing?
What is reference-based analysis?
What is the cost of the test?
What sample is required?
How long does it take to get results?
Is fasting required?
Can this test detect antibiotic resistance?
Is home sample collection available?
What are the common symptoms of bacterial infections?
How is this test different from standard culture?
Who should consider this test?
Is the test covered by insurance?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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