Breast Cancer ER PR HER-2 Ki-67 Test
Short Name: Breast Cancer Biomarkers Panel
Also known as: ER/PR/HER2/Ki67 Test, Breast Cancer Receptor Panel, Breast Cancer Biomarker Analysis
Breast Cancer ER PR HER-2 Ki-67 Test test available at DNA Labs India for ₹14,000. Uses Immunohistochemistry on Tumor Tissue samples. Results in 10 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To determine the presence and status of ER, PR, HER-2, and Ki-67 in breast cancer tissues, aiding in diagnosis, prognosis, treatment planning, and monitoring of breast cancer.
- Test Code
- 8
- Price
- ₹14,000
- Sample Type
- Tumor Tissue
- Result Time
- 10 days
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Ensure a histopathology report, clinical history, and site of biopsy are available. No specific patient preparation required.
Method: Surgical or biopsy sample collection
Laboratory Analysis
Tumor tissue sample is collected via biopsy or surgical excision under sterile conditions.
Report Delivery
Sample is preserved in 10% formal-saline or FFPE block and shipped at room temperature to the lab.
Timeline: 10 days
Patient Instructions
About This Test
Who Should Get This Test
To determine the presence and status of ER, PR, HER-2, and Ki-67 in breast cancer tissues, aiding in diagnosis, prognosis, treatment planning, and monitoring of breast cancer.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded (FFPE) block
- Ship sample at room temperature
- Provide a copy of the Histopathology report, Clinical history, and indicate site of biopsy
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test provides critical biomarker information for personalized treatment plans in breast cancer, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate or unlabeled specimen
- Sample not in proper fixative
- Missing clinical information or histopathology report
- Insufficient tumor tissue for analysis
Understanding Your Results
Positive: Tumor may respond to hormone therapy (e.g., tamoxifen). Negative: Hormone therapy unlikely to be effective.
Positive: Indicates hormone receptor positivity, supporting hormone therapy use. Negative: Similar to ER negative, less likely to benefit from hormone therapy.
Positive: Tumor may benefit from targeted therapies like trastuzumab. Negative: Targeted therapy not indicated. Equivocal: Further testing with FISH recommended.
High (≥14%): Indicates high proliferation rate, may suggest more aggressive cancer and consider chemotherapy. Low (<14%): Lower proliferation, often associated with better prognosis.
Consult your oncologist immediately after receiving test results to discuss treatment options, especially if biomarkers indicate aggressive cancer or need for targeted therapy.
Limitations
- ⚠Requires sufficient tumor tissue from biopsy or surgery
- ⚠Not a screening test; used after clinical suspicion
- ⚠Results may vary based on tumor heterogeneity
- ⚠Does not detect all breast cancer subtypes
Risks & Considerations
- ●Minor bleeding or infection at biopsy site
- ●Rare allergic reactions to local anesthesia
- ●False positives or negatives due to sample quality
Interfering Factors
- ●Poor tissue fixation or processing
- ●Sampling error or inadequate tumor content
- ●Technical issues in staining or interpretation
- ●Use of certain medications that may affect biomarker expression
Compare With Similar Tests
| Test | Breast Cancer ER PR HER-2 Ki-67 | Mammography | Breast Ultrasound | MRI Breast | BRCA Genetic Test |
|---|---|---|---|---|---|
| Comparison | Breast Cancer ER PR HER-2 Ki-67 |
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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