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DNA Labs India

C5 Complement Test

DNA Labs India | ISO 9001:2015 Certified

C5 Complement Test

Also known as: C5 Complement Assay, Complement C5 Test

C5 Complement Test test available at DNA Labs India for ₹12,000. Uses Radial Immunodiffusion on Serum samples. Results in Results are typically available within 2-3 weeks after sample collection.. Free home collection in 300+ cities across India.

Blood Test🏠 Home Collection

Overview

The primary purpose of the C5 Complement Test is to diagnose C5 Complement Deficiency by quantifying C5 protein levels in the blood. This helps in identifying immune system abnormalities, guiding treatment for recurrent infections and autoimmune conditions, and assessing genetic risk factors.

Test Code
235
Price
₹12,000
Sample Type
Serum
Result Time
Results are typically available within 2-3 weeks after sample collection.
Fasting Required
No
Method
Radial Immunodiffusion
Step 1

Sample Collection

Ensure the Test Send Out Consent Form (Form 35) is duly filled. No fasting required, but inform the physician about any medications or health conditions.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm. The process is quick and minimally invasive, performed by trained phlebotomists.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise. Monitor for any signs of infection or excessive bruising.

Timeline: Results are typically available within 2-3 weeks after sample collection.

Patient Instructions

1
Before the Test:No special preparation is needed. Ensure consent form is completed and inform the lab about any relevant medical history.
2
During the Test:The test involves a standard blood draw. It is a quick procedure with minimal discomfort.
3
After the Test:You can resume normal activities immediately. Results will be available in 2-3 weeks.

About This Test

Who Should Get This Test

The primary purpose of the C5 Complement Test is to diagnose C5 Complement Deficiency by quantifying C5 protein levels in the blood. This helps in identifying immune system abnormalities, guiding treatment for recurrent infections and autoimmune conditions, and assessing genetic risk factors.

How to Prepare

  • Duly filled Test Send Out Consent Form (Form 35) is mandatory.
  • Sample should be collected in a serum separator tube.
  • Ship sample refrigerated or frozen to maintain stability.
  • Avoid hemolysis during blood draw.

Doctor's Notes

"The C5 Complement Test is essential for patients with recurrent infections or autoimmune symptoms to identify underlying complement deficiency, enabling early intervention and management."

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 6 hours
Refrigerator: 28 days
Frozen: 30 days
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Incorrect sample type or volume
  • Missing consent form

Understanding Your Results

Interpretation of C5 Complement Test results involves comparing the measured C5 protein level to the reference range. Low levels indicate C5 Complement Deficiency, which may require further evaluation and management.
📊

Low C5 Level

Suggestive of C5 Complement Deficiency. Correlate with clinical symptoms and family history. Consider genetic counseling and immune system evaluation.

Action: Consult an immunologist for comprehensive assessment.

📊

Normal C5 Level

Indicates normal C5 complement function. Symptoms may be due to other causes; further testing may be needed.

Action: Discuss results with your physician for appropriate next steps.

📊

High C5 Level

May occur in acute inflammation or infection. Not specific to deficiency but warrants clinical correlation.

Action: Monitor symptoms and repeat test if necessary.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience recurrent infections, unexplained inflammation, autoimmune symptoms, or have a family history of complement deficiency. Seek immediate care for signs of severe infection like high fever or meningitis symptoms.

Limitations

  • Does not assess other complement components
  • May require confirmatory genetic testing
  • Results can be influenced by acute inflammation

Risks & Considerations

  • Minor bruising or pain at the puncture site
  • Rare risk of infection
  • Fainting or dizziness in some individuals

Interfering Factors

  • Hemolyzed samples
  • Recent immunosuppressive therapy
  • Certain medications like corticosteroids

Compare With Similar Tests

TestC5 Complement TestC3 Complement TestTotal Complement Activity (CH50)
ComparisonC5 Complement Test

Frequently Asked Questions

What is the C5 Complement Test?
The C5 Complement Test is a blood test that measures the level of C5 complement protein, which is part of the immune system. It helps diagnose C5 Complement Deficiency.
Why is the C5 Complement Test recommended?
It is recommended for individuals with recurrent infections, autoimmune disorders, or a family history of complement deficiency to identify immune system abnormalities.
What are the symptoms of C5 Complement Deficiency?
Symptoms include recurrent respiratory and urinary infections, increased susceptibility to bacterial infections, skin and joint inflammation, autoimmune diseases like lupus, and risk of meningitis.
How is the C5 Complement Test performed?
The test involves drawing a blood sample from a vein in the arm. The sample is then analyzed in a lab using radial immunodiffusion to measure C5 levels.
What sample is required for the C5 Complement Test?
A serum sample of 2 mL (minimum 1 mL) collected in a serum separator tube (SST) is required.
Is fasting required for the C5 Complement Test?
No fasting is required, but a duly filled Test Send Out Consent Form (Form 35) is mandatory.
How long does it take to get results for the C5 Complement Test?
Results are typically available within 2-3 weeks after sample collection.
What is the cost of the C5 Complement Test at DNA Labs India?
The cost is INR 12000, which includes home collection, testing, and report delivery.
Is home sample collection available for the C5 Complement Test?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
How accurate is the C5 Complement Test?
The test is accurate and reliable when performed using standard methods like radial immunodiffusion, but results should be interpreted by a healthcare professional.
What should I do if my C5 Complement Test results are abnormal?
Consult an immunologist or your physician for further evaluation, which may include genetic testing or additional immune system assessments.
Can the C5 Complement Test detect other conditions?
The test specifically measures C5 protein levels. Abnormal results may indicate complement deficiency, but other conditions like infections or inflammation can also affect levels, requiring clinical correlation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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