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CACNA1C Gene Long QT syndrome type 8 NGS Genetic Test

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CACNA1C Gene Long QT syndrome type 8 NGS Genetic Test

Short Name: CACNA1C LQTS Type 8 NGS Test

Also known as: Long QT Syndrome Type 8, LQTS Type 8, CACNA1C-related LQTS, Timothy Syndrome Type 2

CACNA1C Gene Long QT syndrome type 8 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS), Sanger Sequencing for confirmation on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the CACNA1C gene that cause Long QT Syndrome Type 8, enabling early diagnosis, risk assessment, and personalized management to prevent life-threatening cardiac events.

Test Code
2542
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS), Sanger Sequencing for confirmation
Step 1

Sample Collection

No specific preparation required. Inform healthcare provider about any medications or medical conditions.

Method: Venipuncture or finger-prick

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm or a finger-prick for FTA card collection.

Step 3

Report Delivery

Apply pressure to the collection site to prevent bleeding. Resume normal activities.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss test implications, family history, and consent.
2
During the Test:Sample collection via blood draw or FTA card, followed by NGS analysis in the laboratory.
3
After the Test:Results delivered in 3-4 weeks. Follow-up genetic counseling recommended for result interpretation.

About This Test

Who Should Get This Test

To identify mutations in the CACNA1C gene that cause Long QT Syndrome Type 8, enabling early diagnosis, risk assessment, and personalized management to prevent life-threatening cardiac events.

How to Prepare

  • Ensure proper identification of patient
  • Use sterile collection equipment
  • Label samples correctly
  • Transport samples at room temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for LQTS Type 8 is essential for identifying at-risk individuals and guiding personalized treatment plans to prevent sudden cardiac events."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the CACNA1C gene. Positive results confirm LQTS Type 8 diagnosis, while negative results may require further clinical evaluation.
📊

Positive for pathogenic mutation

Confirms diagnosis of LQTS Type 8. Genetic counseling and cardiac monitoring recommended.

📊

Negative for pathogenic mutation

No mutations detected in CACNA1C gene. Clinical correlation needed if symptoms persist.

📊

Variant of uncertain significance

Further testing and family studies may be required for clarification.

⚠️ When to Consult a Doctor:

If symptoms such as fainting, palpitations, or seizures occur, or if there is a family history of sudden cardiac death, consult a cardiologist or geneticist immediately.

Limitations

  • ⚠May not detect all possible mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results may have variants of uncertain significance

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Hemolyzed blood samples

Compare With Similar Tests

TestCACNA1C Gene Long QT syndrome type 8 NGS Genetic TestKCNQ1 Gene LQTS TestKCNH2 Gene LQTS TestSCN5A Gene LQTS TestComprehensive LQTS Panel
ComparisonCACNA1C Gene Long QT syndrome type 8 NGS Genetic Test

Frequently Asked Questions

What is CACNA1C Gene Long QT Syndrome Type 8?
It is a genetic cardiac disorder caused by mutations in the CACNA1C gene, leading to prolonged QT interval and risk of arrhythmias.
What are the symptoms of LQTS Type 8?
Symptoms include fainting, heart palpitations, seizures, and potentially cardiac arrest or sudden death.
How is LQTS Type 8 diagnosed?
Diagnosis involves ECG, medical history, and genetic testing to identify mutations in the CACNA1C gene.
What is the cost of the NGS Genetic Test for LQTS Type 8?
The cost is INR 20000 at DNA Labs India, with home sample collection available.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection across many cities in India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result confirms a mutation in the CACNA1C gene, indicating LQTS Type 8, requiring cardiac monitoring and management.
Is genetic counseling required before testing?
Yes, genetic counseling is recommended to understand the implications, family risks, and consent process.
Can this test be done for children?
Yes, the test can be performed on individuals of all ages, including children, with appropriate consent.
What are the risks of the genetic test?
Risks are minimal, primarily related to blood draw, such as bruising. Psychological impact of results should be considered.
Is the test covered by insurance?
Coverage varies by insurance provider. It is advisable to check with your insurance company before testing.
How accurate is the NGS genetic test?
NGS is highly accurate for detecting mutations, but results should be interpreted in conjunction with clinical findings and genetic counseling.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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