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CALR3 Gene Cardiomyopathy, familial hypertrophic type 19 NGS Genetic Test

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CALR3 Gene Cardiomyopathy, familial hypertrophic type 19 NGS Genetic Test

Short Name: CALR3 Cardiomyopathy NGS Test

Also known as: CALR3 Gene Test, Hypertrophic Cardiomyopathy Type 19 Genetic Test

CALR3 Gene Cardiomyopathy, familial hypertrophic type 19 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the CALR3 gene associated with familial hypertrophic cardiomyopathy type 19, aiding in diagnosis, risk assessment, and management of the condition.

Test Code
2527
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required, but genetic counseling is recommended prior to testing.

Method: Venipuncture or FTA card

Step 2

Laboratory Analysis

A blood sample will be drawn by a trained phlebotomist using standard venipuncture techniques or a FTA card for one-drop blood collection.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding and avoid strenuous activity for a few hours.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Schedule a genetic counseling session to discuss the test, implications, and family history.
2
During the Test:Sample collection takes about 10-15 minutes; the process is minimally invasive.
3
After the Test:Wait for results, which will be delivered online; follow up with a healthcare provider for interpretation.

About This Test

Who Should Get This Test

To identify mutations in the CALR3 gene associated with familial hypertrophic cardiomyopathy type 19, aiding in diagnosis, risk assessment, and management of the condition.

How to Prepare

  • Bring a doctor's prescription and valid ID
  • Ensure proper identification and labeling of samples
  • Follow any specific instructions from the healthcare provider

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for CALR3 can aid in early diagnosis and management of familial hypertrophic cardiomyopathy, especially in families with a history of cardiac issues."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs per requirement
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card

Sample Stability

Blood sample stable for 48 hours at 2-8°C
FTA card stable at room temperature for extended periods
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Incorrect sample type or container
  • Insufficient sample volume
  • Unlabeled or mislabeled samples

Understanding Your Results

Results indicate the presence or absence of mutations in the CALR3 gene, which can help diagnose familial hypertrophic cardiomyopathy type 19.
📊

Mutation detected

Suggests a genetic predisposition to familial hypertrophic cardiomyopathy type 19; further clinical evaluation and family screening recommended.

📊

No mutation detected

No pathogenic variant found in the CALR3 gene; does not rule out other genetic or non-genetic causes of cardiomyopathy.

⚠️ When to Consult a Doctor:

If you experience symptoms like chest pain, shortness of breath, or have a family history of cardiomyopathy, consult a cardiologist or genetic specialist for evaluation.

Limitations

  • ⚠Only detects mutations in the CALR3 gene; may not identify other genetic causes of cardiomyopathy
  • ⚠Results require interpretation by a genetic counselor or healthcare provider
  • ⚠False negatives possible if mutations are in non-coding regions not covered by the test

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Emotional impact of genetic results; counseling available

Interfering Factors

  • ●Hemolyzed blood sample
  • ●Insufficient DNA quality or quantity
  • ●Contamination during sample handling

Compare With Similar Tests

TestCALR3 Gene Cardiomyopathy, familial hypertrophic type 19 NGS Genetic TestMYH7 Gene Cardiomyopathy TestTNNT2 Gene Cardiomyopathy TestCardiac MRI
ComparisonCALR3 Gene Cardiomyopathy, familial hypertrophic type 19 NGS Genetic Test

Frequently Asked Questions

What is the CALR3 Gene Cardiomyopathy NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the CALR3 gene, associated with familial hypertrophic cardiomyopathy type 19.
Why is this test important?
It helps diagnose a genetic heart condition, assess risk for family members, and guide treatment and management strategies.
What are the symptoms of CALR3 gene cardiomyopathy?
Symptoms may include chest pain, shortness of breath, fatigue, dizziness, irregular heartbeat, and fainting episodes.
How is the test performed?
A blood sample or extracted DNA is collected and analyzed using NGS technology in a certified laboratory.
What is the cost of the test?
The test costs INR 20000 at DNA Labs India, with home sample collection available.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings across many cities in India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates a mutation in the CALR3 gene, suggesting a genetic predisposition to familial hypertrophic cardiomyopathy type 19.
What does a negative result mean?
A negative result means no pathogenic variant was found in the CALR3 gene, but it does not rule out other causes of cardiomyopathy.
Is genetic counseling required?
Genetic counseling is recommended before and after testing to understand implications and interpret results accurately.
Is the test covered by insurance?
Coverage varies; check with your insurance provider. DNA Labs India offers the test at a discounted price.
How accurate is the NGS genetic test?
NGS technology is highly accurate for detecting genetic mutations, but results should be interpreted by a qualified healthcare professional.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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