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DNA Labs India

CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test

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CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test

Short Name: CELSR2 Schizophrenia NGS

Also known as: CELSR2 schizophrenia genetic test, CELSR2-related NGS genetic test, CELSR2 gene sequencing for schizophrenia

CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are delivered within 3 to 4 weeks from the date the sample is received by the laboratory.. Free home collection in 300+ cities across India.

NGS Genetic TestAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose is to detect disease-associated sequence variants in the CELSR2 gene that may contribute to an individual’s risk for schizophrenia and help guide personalized clinical management and genetic counseling.

Test Code
4500
ICD Code
F20.9
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Reports are delivered within 3 to 4 weeks from the date the sample is received by the laboratory.
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

No fasting is required. Patients should bring any prior genetic counselling records, psychiatric assessment documents, and a valid doctor's prescription if available.

Method: Peripheral venipuncture or FTA card blood spot

Step 2

Laboratory Analysis

A small sample of blood is drawn from a vein in the arm, or one drop of blood is applied to an FTA card. The procedure is non-invasive and usually painless.

Step 3

Report Delivery

You may return to normal activities immediately. If an FTA card was used, it should be kept dry and in the provided packaging until it reaches the laboratory.

Timeline: Reports are delivered within 3 to 4 weeks from the date the sample is received by the laboratory.

Patient Instructions

1
Before the Test:No special preparation is required. A pretest genetic counselling session is recommended and is included with this test.
2
During the Test:The NGS analysis is performed on the extracted DNA after sample collection. You are not required to do anything during the laboratory analysis.
3
After the Test:Once the report is ready, it is shared securely through the chosen delivery option. A follow-up consultation with your doctor is advised to understand the implications.

About This Test

Who Should Get This Test

The purpose is to detect disease-associated sequence variants in the CELSR2 gene that may contribute to an individual’s risk for schizophrenia and help guide personalized clinical management and genetic counseling.

How to Prepare

  • Maintain normal food and water intake before sampling
  • Ensure sample collection is performed by trained phlebotomist or following provided FTA card kit instructions
  • Label the sample container/Card with patient name and ID
  • Inform the lab about any previous genetic testing for schizophrenia

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"A positive genetic variant must be correlated with family history and psychosocial assessment. This is not a standalone diagnostic result."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume2-3 mL blood; 1 blood spot on FTA card; 1-2 µg extracted DNA
ContainerEDTA whole blood tube / DNA vial / FTA card
Collection MethodPeripheral venipuncture or FTA card blood spot

Sample Stability

Whole blood in EDTA: transport and process within 48 hours at room temperature
Extracted DNA: stable at -20°C for long-term storage
FTA card: stable at room temperature when stored dry
Sample Rejection Criteria:
  • Improperly labeled samples
  • Clotted or hemolyzed blood samples
  • FTA card not dried before sealing
  • Insufficient DNA quantity or quality for NGS

Understanding Your Results

The test looks for sequence variants in the CELSR2 gene that are associated with increased risk for schizophrenia. Results should be interpreted in the context of clinical symptoms, family history, and the opinion of a qualified mental health professional.
📊

Positive

A pathogenic or likely pathogenic variant was detected in the CELSR2 gene. This indicates increased susceptibility, not a diagnosis of schizophrenia.

📊

Negative

No pathogenic or likely pathogenic variant was detected in the CELSR2 gene. Genetic risk from other genes or non-genetic factors may still be present.

📊

Variant of Uncertain Significance

A variant was found, but it is not yet known whether it is disease-associated. Further family studies may be recommended.

⚠️ When to Consult a Doctor:

If your result is positive or a variant of uncertain significance, please consult your referring doctor and a clinical geneticist for a detailed discussion and follow-up plan.

Limitations

  • This test only analyzes the CELSR2 gene and does not exclude variants in other genes associated with schizophrenia.
  • NGS may not detect all structural rearrangements, large deletions, or deep intronic variants.
  • Variants of uncertain significance may be reported and require additional family studies.

Risks & Considerations

  • Slight pain, bruising, or discomfort at the blood collection site
  • Potential psychological distress or anxiety from genetic risk information
  • Rare possibility of incidental findings unrelated to the primary question

Interfering Factors

  • Insufficient or degraded DNA
  • Maternal cell contamination in prenatal or umbilical cord samples
  • Incorrect anticoagulant or sample mix-up

Frequently Asked Questions

What is the cost of the CELSR2 gene schizophrenia NGS genetic test?
The test costs INR 20,000. Home sample collection is free when booked online.
What sample is needed for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required before the test?
No, fasting is not required for this DNA-based test.
What does the test detect?
The test detects sequence changes in the CELSR2 gene that have been associated with increased schizophrenia risk.
Does a positive result mean I will develop schizophrenia?
No. A positive result indicates increased susceptibility, but it does not confirm that schizophrenia will develop. Clinical assessment is required.
Can this test diagnose schizophrenia?
No. Schizophrenia is diagnosed clinically. Genetic testing is a supportive tool to understand risk.
Why is genetic counselling included?
Genetic counselling helps review family history, explain potential implications, and guide medical decisions.
How long does it take to get the report?
Reports are delivered in 3 to 4 weeks after the sample is received at the laboratory.
Is this test available all over India?
Yes, DNA Labs India offers home sample collection in over 300 cities across India.
Will my insurance cover this test?
Coverage depends on your insurance provider and plan. Most insurers do not cover genetic susceptibility testing unless medically recommended and pre-approved.
What is the difference between this test and a full schizophrenia panel?
This test focuses only on the CELSR2 gene, whereas a full panel evaluates multiple genes linked to schizophrenia.
What should I do if my result is positive?
You should consult your referring doctor and a clinical geneticist for further evaluation and risk management.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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