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Chromosome Analysis for Hematologic Malignancy Test

DNA Labs India | ISO 9001:2015 Certified

Chromosome Analysis for Hematologic Malignancy Test

Short Name: Chromosome Analysis Test

Also known as: Karyotyping, Chromosome Karyotype Analysis

Chromosome Analysis for Hematologic Malignancy Test test available at DNA Labs India for ₹5,000. Uses Culture, Robotic Microscopy, Karyotype on Bone Marrow or Whole Blood samples. Results in 4 Working days. Free home collection in 300+ cities across India.

Diagnostic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To identify chromosomal abnormalities associated with hematologic malignancies for accurate diagnosis, prognosis, and treatment planning.

Test Code
305
Price
₹5,000
Sample Type
Bone Marrow or Whole Blood
Result Time
4 Working days
Fasting Required
No
Method
Culture, Robotic Microscopy, Karyotype
Step 1

Sample Collection

Ensure the Chromosome & FISH Analysis Requisition form (Form 17) is duly filled and signed by the referring physician.

Method: Phlebotomy or Bone Marrow Aspiration

Step 2

Laboratory Analysis

Sample collection by a trained phlebotomist or hematologist; bone marrow aspiration may involve local anesthesia.

Step 3

Report Delivery

Sample must be refrigerated immediately and shipped to the lab without freezing to ensure cell viability.

Timeline: 4 Working days

Patient Instructions

1
Before the Test:No special preparation is required, but ensure the requisition form is completed and bring any relevant medical records.
2
During the Test:The sample collection procedure takes a few minutes; bone marrow aspiration may involve brief discomfort.
3
After the Test:Mild soreness at the collection site is normal; resume normal activities unless advised otherwise. Results are available in 4 working days.

About This Test

Who Should Get This Test

To identify chromosomal abnormalities associated with hematologic malignancies for accurate diagnosis, prognosis, and treatment planning.

How to Prepare

  • Duly fill Chromosome & FISH Analysis Requisition form (Form 17)
  • Use 3 mL whole blood in Green Top (Sodium Heparin) tube or 1.5 mL heparinized bone marrow
  • Ship refrigerated immediately, do not freeze
  • Specimen must reach the lab within 24 hours

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is crucial for identifying chromosomal abnormalities in hematologic malignancies, aiding in accurate diagnosis, staging, and personalized treatment planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBone Marrow or Whole Blood
Sample Volume1.5 mL min. for bone marrow, 2 mL min. for blood
ContainerGreen Top (Sodium Heparin) tube
Collection MethodPhlebotomy or Bone Marrow Aspiration

Sample Stability

Refrigerated (2-8°C): 24 hours
Frozen: Unacceptable
Sample Rejection Criteria:
  • Frozen samples
  • Insufficient sample volume
  • Incorrect container or anticoagulant
  • Missing or incomplete requisition form

Understanding Your Results

Results from the Chromosome Analysis test indicate the presence or absence of chromosomal abnormalities, which are key to diagnosing hematologic malignancies.
Normal: No chromosomal abnormalities detected, indicating a typical karyotype
Abnormal: Specific chromosomal changes identified, such as translocations (e.g., Philadelphia chromosome) or deletions, which may confirm hematologic malignancy
Inconclusive: Repeat testing may be required due to insufficient cell growth or technical issues
⚠️ When to Consult a Doctor:

Consult a hematologist or oncologist if you experience persistent symptoms like fatigue, weight loss, or swollen lymph nodes, or if test results indicate abnormalities.

Limitations

  • ⚠May not detect all genetic or molecular abnormalities
  • ⚠Requires viable cultured cells
  • ⚠Turnaround time of 4 working days
  • ⚠Limited to chromosomal level analysis

Risks & Considerations

  • ●Pain or discomfort during sample collection
  • ●Risk of infection or bruising at the site
  • ●Rare allergic reactions to anticoagulant

Interfering Factors

  • ●Sample contamination
  • ●Improper sample handling
  • ●Delayed processing
  • ●Use of incorrect anticoagulant

Frequently Asked Questions

What is the Chromosome Analysis for Hematologic Malignancy Test?
It is a diagnostic test that examines chromosomes in blood or bone marrow cells to identify abnormalities associated with blood cancers like leukemia or lymphoma.
How is the sample collected for this test?
Sample is collected via phlebotomy for blood or bone marrow aspiration, using a sodium heparin tube, and must be shipped refrigerated to the lab within 24 hours.
What is the cost of the test in India?
The cost is INR 5000 at DNA Labs India, with free home sample collection available in many cities across India.
Does DNA Labs India offer home sample collection?
Yes, free home sample collection is available for online bookings in various cities, including Mumbai, Delhi, Bangalore, and more.
How long does it take to receive the test results?
Results are typically available within 4 working days after the sample reaches the lab.
What symptoms indicate the need for this test?
Symptoms like fever, fatigue, unexplained weight loss, night sweats, swollen lymph nodes, easy bruising, or shortness of breath may warrant testing.
What does a normal result mean?
A normal result shows no chromosomal abnormalities, but clinical correlation is needed as some malignancies may not be detected at the chromosomal level.
What if the test shows chromosomal abnormalities?
Abnormalities help diagnose specific types of hematologic malignancy, guiding treatment options such as targeted therapy or chemotherapy.
Are there any risks associated with the test?
Risks include minor pain, bruising, or infection at the collection site; bone marrow aspiration may involve more discomfort.
How should I prepare for the test?
No special preparation is needed, but ensure the requisition form (Form 17) is filled out by your doctor before sample collection.
Is the test covered under government health schemes?
Coverage varies by scheme like PMJAY, CGHS, etc.; it is advisable to check with the specific scheme or insurance provider for details.
Who should I consult for interpreting the results?
Consult a hematologist or oncologist who can interpret the results in the context of your symptoms and medical history.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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