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CYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic Test

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CYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic Test

Short Name: CYP3A5 Gene Test

Also known as: CYP3A5 Hypertension Test, Salt-Sensitive Hypertension Genetic Test

CYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood, Extracted DNA, or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify genetic susceptibility to salt-sensitive hypertension through CYP3A5 gene analysis, enabling early intervention and personalized management.

Test Code
5329
Price
₹20,000
Sample Type
Blood, Extracted DNA, or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Consult with a genetic counselor if needed.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Blood sample will be drawn by a trained phlebotomist using sterile equipment.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Keep the area clean.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Consult with a genetic counselor to understand the implications of testing and draw a family pedigree chart.
2
During the Test:Sample collection procedure involves drawing blood or using an FTA card for DNA extraction.
3
After the Test:Wait for results as per the turnaround time. Follow up with a healthcare provider for interpretation.

About This Test

Who Should Get This Test

To identify genetic susceptibility to salt-sensitive hypertension through CYP3A5 gene analysis, enabling early intervention and personalized management.

How to Prepare

  • Ensure proper patient identification
  • Use aseptic technique
  • Label samples correctly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for CYP3A5 can help identify individuals at risk for salt-sensitive hypertension, allowing for early lifestyle interventions to manage blood pressure."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood samples stable for 24 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of CYP3A5 gene variants associated with salt-sensitive hypertension.
📊

Variant detected

Increased genetic susceptibility to salt-sensitive hypertension. Recommend lifestyle modifications and regular monitoring.

📊

No variant detected

Standard genetic risk for salt-sensitive hypertension. Maintain healthy habits and routine blood pressure checks.

⚠️ When to Consult a Doctor:

If you have a family history of hypertension, experience symptoms like headaches or dizziness, or have been diagnosed with high blood pressure, consult a doctor for evaluation and possible genetic testing.

Limitations

  • ⚠Does not diagnose hypertension directly
  • ⚠Genetic risk is not deterministic; lifestyle factors also play a role

Risks & Considerations

  • ●Minor bruising at puncture site
  • ●Rare risk of infection
  • ●Emotional impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Technical errors in sequencing

Compare With Similar Tests

TestCYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic Test
ComparisonCYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic Test

Frequently Asked Questions

What is the CYP3A5 gene?
The CYP3A5 gene produces an enzyme involved in drug metabolism and blood pressure regulation. Variations in this gene are associated with salt-sensitive hypertension.
What is salt-sensitive hypertension?
Salt-sensitive hypertension is a type of high blood pressure that increases in response to high salt intake, affecting about 50% of individuals with essential hypertension.
How does the CYP3A5 gene affect blood pressure?
Variations in the CYP3A5 gene can lead to increased susceptibility to salt-sensitive hypertension by influencing how the body handles sodium and regulates blood pressure.
Who should consider this genetic test?
Individuals with a family history of hypertension, those from African or Hispanic descent, or those with symptoms like headaches or dizziness should consider testing.
How is the test performed?
The test uses Next-Generation Sequencing (NGS) technology to analyze the CYP3A5 gene from a blood sample or extracted DNA.
What sample is required for the test?
A blood sample, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the test results mean?
Results indicate whether pathogenic variants in the CYP3A5 gene are detected, which may increase risk for salt-sensitive hypertension. Consult a doctor for interpretation.
Can this test diagnose hypertension?
No, this test identifies genetic susceptibility but does not diagnose hypertension directly. Blood pressure measurement is needed for diagnosis.
Is genetic testing for hypertension covered by insurance?
Coverage varies by insurance plan. Check with your provider for details on genetic testing coverage.
How can I book the test?
You can book the test online through DNA Labs India's website, with free home sample collection available across many cities in India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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