DLX3 Gene Amelogenesis imperfecta type 4 NGS Genetic Test
Short Name: DLX3 AI4 NGS Genetic Test
Also known as: Amelogenesis Imperfecta Type 4, AI4, DLX3-related Amelogenesis Imperfecta
DLX3 Gene Amelogenesis imperfecta type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood, Extracted DNA, or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the DLX3 Gene Amelogenesis Imperfecta Type 4 NGS Genetic Test is to identify mutations in the DLX3 gene that cause amelogenesis imperfecta type 4. This test aids in accurate diagnosis, guides treatment and management strategies, supports genetic counseling for affected families, and helps in understanding the inheritance pattern of the condition.
- Test Code
- 4840
- Price
- ₹20,000
- Sample Type
- Blood, Extracted DNA, or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No specific preparation required. Provide clinical history and undergo genetic counseling if recommended.
Method: Venipuncture for blood or DNA extraction
Laboratory Analysis
A blood sample will be drawn from a vein in the arm, or a saliva sample may be collected using a kit.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store samples as instructed and send to the laboratory promptly.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the DLX3 Gene Amelogenesis Imperfecta Type 4 NGS Genetic Test is to identify mutations in the DLX3 gene that cause amelogenesis imperfecta type 4. This test aids in accurate diagnosis, guides treatment and management strategies, supports genetic counseling for affected families, and helps in understanding the inheritance pattern of the condition.
How to Prepare
- Ensure proper identification of the patient
- Use sterile collection equipment
- Label samples correctly
- Follow transport guidelines for sample stability
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for AI4 can guide treatment, management, and family planning decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Contaminated samples
- Improperly labeled samples
Understanding Your Results
Positive for DLX3 mutation
Confirms diagnosis of amelogenesis imperfecta type 4. Genetic counseling and tailored dental management are recommended.
Negative for DLX3 mutation
No pathogenic variants detected in the DLX3 gene. Clinical correlation and additional tests may be needed.
Variant of uncertain significance
A genetic variant was found but its clinical significance is unknown. Further evaluation and family studies may be required.
Consult a dentist or genetic counselor if you experience symptoms of AI4, have a family history of the condition, or receive a positive genetic test result for guidance on treatment and management.
Limitations
- ⚠May not detect all possible mutations in the DLX3 gene
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical findings
- ⚠Not a substitute for comprehensive dental examination
Risks & Considerations
- ●Minimal risks from blood draw, such as bruising or infection
- ●Psychological impact of genetic diagnosis
- ●Potential for uncertain results requiring further investigation
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Improper sample storage
- ●Recent blood transfusion
Compare With Similar Tests
| Test | DLX3 Gene Amelogenesis imperfecta type 4 NGS Genetic Test | AMELX Gene Test | ENAM Gene Test | MMP20 Gene Test | KLK4 Gene Test |
|---|---|---|---|---|---|
| Comparison | DLX3 Gene Amelogenesis imperfecta type 4 NGS Genetic Test |
Frequently Asked Questions
What is amelogenesis imperfecta type 4 (AI4)?
What causes AI4?
What are the symptoms of AI4?
How is AI4 diagnosed?
What is the DLX3 Gene AI4 NGS Genetic Test?
How is the test performed?
What is the cost of the test?
Is home sample collection available?
How long does it take to get results?
Is the test covered by insurance?
What should I do after receiving a positive result?
Can AI4 be treated?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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