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DSPP Gene Dentin dysplasia, type 2 NGS Genetic Test

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DSPP Gene Dentin dysplasia, type 2 NGS Genetic Test

Also known as: Dentin dysplasia type II, DSPP-related dentin dysplasia

DSPP Gene Dentin dysplasia, type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the DSPP gene for definitive diagnosis of dentin dysplasia type 2, enabling early intervention and informed family planning.

Test Code
4885
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history review and genetic counseling session recommended to draw a pedigree chart.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collection via venipuncture or use of FTA card for one drop of blood.

Step 3

Report Delivery

Sample is processed and analyzed using NGS technology in the laboratory.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and informed consent are required before testing.
2
During the Test:Blood sample collection is performed by a trained phlebotomist.
3
After the Test:Wait for results and schedule a follow-up with a healthcare provider for interpretation.

About This Test

Who Should Get This Test

To identify mutations in the DSPP gene for definitive diagnosis of dentin dysplasia type 2, enabling early intervention and informed family planning.

How to Prepare

  • Ensure proper sample labeling with patient details
  • Follow aseptic techniques during blood collection
  • For FTA card, apply one drop of blood and allow to dry

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for DSPP gene mutations is crucial for definitive diagnosis and management of dentin dysplasia type 2, aiding in early intervention and family planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood samples stable at room temperature for up to 24 hours
Extracted DNA stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Hemolyzed or contaminated samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the DSPP gene, which are associated with dentin dysplasia type 2.
📊

Pathogenic variant detected

Confirms diagnosis of dentin dysplasia type 2. Genetic counseling and dental management recommended.

📊

No pathogenic variant detected

DSPP gene mutations not found. Consider other genetic or non-genetic causes of dental anomalies.

⚠️ When to Consult a Doctor:

If symptoms of dentin dysplasia are present, for family planning advice, or to discuss test results and management options.

Limitations

  • ⚠Test only detects mutations in the DSPP gene
  • ⚠May not identify all genetic causes of dentin dysplasia
  • ⚠Requires genetic counseling for accurate interpretation
  • ⚠Results may have implications for family members

Risks & Considerations

  • ●Minimal risk associated with blood draw, such as bruising or infection
  • ●Potential psychological impact of genetic results on individuals and families

Frequently Asked Questions

What is dentin dysplasia type 2?
Dentin dysplasia type 2 is a rare genetic condition that affects tooth development, caused by mutations in the DSPP gene, leading to abnormal dentin formation.
What causes dentin dysplasia type 2?
It is caused by mutations in the DSPP gene, which provides instructions for making dentin sialophosphoprotein, essential for dentin formation.
How is the NGS genetic test performed?
The test uses Next-Generation Sequencing (NGS) technology to analyze the DSPP gene from a blood sample or extracted DNA for mutations.
What is the cost of the DSPP gene test in India?
The cost is INR 20,000 at DNA Labs India, with free home sample collection available across many cities.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What are the benefits of genetic testing for dentin dysplasia type 2?
Benefits include accurate diagnosis, early detection before symptoms appear, and informed family planning by assessing inheritance risks.
Who should consider getting this test?
Individuals with symptoms of dentin dysplasia, a family history of the condition, or those seeking genetic counseling for family planning.
What if the test result is positive?
A positive result confirms dentin dysplasia type 2, and genetic counseling along with dental management should be pursued.
Can this test be used for prenatal diagnosis?
This test is typically for postnatal diagnosis; prenatal testing may require specialized genetic counseling and different methods.
Is the test covered by insurance?
Coverage depends on the insurance provider; it is not universally covered, so check with your insurer.
How accurate is the NGS genetic test?
NGS technology provides high accuracy in detecting mutations in the DSPP gene, but results should be interpreted by a genetic specialist.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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