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DNA Labs India

EN2 Gene Autism Spectrum Disorder NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

EN2 Gene Autism Spectrum Disorder NGS Genetic Test

Short Name: EN2 Gene ASD NGS Test

Also known as: EN2 sequencing test for ASD, Engrailed-2 gene test

EN2 Gene Autism Spectrum Disorder NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next Generation Sequencing🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect genetic variations in the EN2 gene associated with Autism Spectrum Disorder, facilitating early diagnosis, risk assessment, and personalized management plans.

Test Code
1528
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Inform the patient about the test and obtain consent. Ensure proper genetic counseling is provided.

Method: Venipuncture

Step 2

Laboratory Analysis

Collect blood sample as per standard venipuncture procedure or use FTA card for one drop blood.

Step 3

Report Delivery

Label the sample correctly and transport to the laboratory under appropriate conditions.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to discuss implications and obtain informed consent.
2
During the Test:Blood sample collection; procedure is similar to standard blood draw.
3
After the Test:Wait for results 3-4 weeks; follow-up with healthcare provider for interpretation.

About This Test

Who Should Get This Test

To detect genetic variations in the EN2 gene associated with Autism Spectrum Disorder, facilitating early diagnosis, risk assessment, and personalized management plans.

How to Prepare

  • Use sterile tubes for blood collection.
  • For FTA card, ensure one drop of blood is applied correctly.
  • Store samples at room temperature if not processing immediately.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for EN2 gene mutations can provide valuable insights into the risk and potential mechanisms of Autism Spectrum Disorder, aiding in early intervention strategies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood samples: Stable for 24 hours at room temperature.
Extracted DNA: Stable for longer periods if stored properly.
Sample Rejection Criteria:
  • Hemolyzed or clotted samples.
  • Insufficient sample volume.
  • Incorrectly labeled samples.

Understanding Your Results

Results should be interpreted by a qualified geneticist or healthcare provider in the context of clinical findings and family history.
Positive result: Pathogenic variant identified in EN2 gene, suggesting increased ASD risk.
Negative result: No pathogenic variants detected; does not rule out ASD due to other genetic factors.
Variant of uncertain significance (VUS): Further testing and clinical correlation recommended.
⚠️ When to Consult a Doctor:

Consult a neurologist or genetic counselor if results indicate a pathogenic variant or if clinical symptoms persist.

Limitations

  • ⚠This test only examines the EN2 gene; ASD is polygenic and influenced by environmental factors.
  • ⚠Results may not definitively diagnose ASD; clinical correlation is required.
  • ⚠Genetic variants of uncertain significance (VUS) may be identified.

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection.
  • ●Psychological impact of genetic results; counseling recommended.

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample type

Compare With Similar Tests

TestEN2 Gene Autism Spectrum Disorder NGS Genetic Test
ComparisonEN2 Gene Autism Spectrum Disorder NGS Genetic TestNon-genetic, focuses on behaviorMay include multiple genes beyond EN2

Frequently Asked Questions

What is the EN2 Gene Autism Spectrum Disorder NGS Genetic Test?
It is a genetic test that uses Next Generation Sequencing to analyze the EN2 gene for variants associated with Autism Spectrum Disorder.
Why is this test recommended?
It helps identify genetic risk factors for ASD, aiding in early diagnosis and personalized management.
How is the sample collected?
Samples can be collected via blood draw or using an FTA card with one drop of blood.
What is the cost of the test?
The test costs INR 20000, including home collection in many cities across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What does a positive result mean?
A positive result indicates a pathogenic variant in the EN2 gene, which may increase ASD risk, but does not alone diagnose ASD.
Can this test diagnose ASD definitively?
No, ASD diagnosis requires clinical evaluation; this test provides genetic insights as part of a comprehensive assessment.
Is genetic counseling required before the test?
Yes, genetic counseling is recommended to discuss implications and obtain informed consent.
Are there any risks associated with the test?
Risks are minimal, related to blood draw, such as bruising; psychological support is advised.
How accurate is the NGS technology for this test?
NGS technology offers high accuracy in sequencing, but results must be interpreted clinically.
What should I do if I have a family history of ASD?
Consider genetic testing and consult a genetic counselor for family risk assessment.
Does insurance cover this test?
Coverage varies; check with your provider. Government schemes like PMJAY may not cover it; verify details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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