F2 Gene Thrombophilia due to thrombin defect NGS Genetic Test
Short Name: F2 Gene Thrombophilia NGS Test
Also known as: Prothrombin Gene Mutation Test, F2 Thrombophilia Genetic Test, Prothrombin G20210A Mutation Test
F2 Gene Thrombophilia due to thrombin defect NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 3, 2026
Overview
The purpose of this test is to detect mutations in the F2 gene that cause thrombophilia, helping to identify individuals at increased risk for blood clots, guide clinical management, and inform family screening.
- Test Code
- 5350
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Inform the healthcare provider about any medications or medical conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in the arm using a needle. For FTA card, a finger prick may be used.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities immediately.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the F2 gene that cause thrombophilia, helping to identify individuals at increased risk for blood clots, guide clinical management, and inform family screening.
How to Prepare
- Ensure proper identification of the patient
- Use sterile collection equipment
- Label samples accurately
- Transport samples at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This NGS test is crucial for identifying genetic predisposition to thrombophilia, enabling personalized management and prevention of blood clots."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrect labeling or documentation
- Contaminated samples
Understanding Your Results
No mutation detected
Low genetic risk for F2-related thrombophilia; clinical correlation recommended.
Heterozygous mutation (e.g., G20210A)
Moderate increased risk for blood clots; consider preventive measures.
Homozygous mutation
High risk for thrombophilia; urgent clinical management and family screening advised.
Consult a doctor if you have a family history of blood clots, experience symptoms like swelling or chest pain, or after receiving positive test results for personalized management.
Limitations
- ⚠This test only analyzes the F2 gene; other thrombophilia genes are not covered
- ⚠Results may not predict clinical outcomes definitively
- ⚠False negatives are possible due to technical limitations
- ⚠Genetic variants of uncertain significance may be detected
Risks & Considerations
- ●Minimal risk from blood draw: bruising, infection, or dizziness
- ●No significant risks from genetic testing itself
Interfering Factors
- ●Sample contamination
- ●Degraded DNA quality
- ●Recent blood transfusions
- ●Use of anticoagulant medications (may affect prothrombin levels)
Compare With Similar Tests
| Test | F2 Gene Thrombophilia due to thrombin defect NGS Genetic Test | Factor V Leiden Mutation Test | Prothrombin Time (PT) Test | Antithrombin III Test | Comprehensive Thrombophilia Panel |
|---|---|---|---|---|---|
| Comparison | F2 Gene Thrombophilia due to thrombin defect NGS Genetic Test | Tests for a different gene mutation causing thrombophilia; often done alongside F2 test. | Measures blood clotting time; not specific for genetic mutations. | Evaluates antithrombin levels; complementary to genetic testing. | Includes multiple genetic tests for a broader assessment. |
Frequently Asked Questions
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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