Factor II Functional Test
Also known as: Prothrombin Activity Test, Factor II Activity Test
Factor II Functional Test test available at DNA Labs India for ₹10,000. Uses Photo-optical Clot Detection on 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. samples. Results in Reports are typically available the next day after sample receipt by 9 am on Thursday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Factor II Functional Test is to evaluate the functional activity of prothrombin in the blood, aiding in the diagnosis of clotting disorders, assessing risk for thrombotic events, and guiding treatment plans for patients with coagulation abnormalities.
- Test Code
- 535
- Price
- ₹10,000
- Sample Type
- 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube.
- Result Time
- Reports are typically available the next day after sample receipt by 9 am on Thursday.
- Fasting Required
- Yes (8 hours)
- Method
- Photo-optical Clot Detection
Sample Collection
Overnight fasting is preferred. Discontinue Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling, with prior consent from the treating physician. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Method: Venipuncture
Laboratory Analysis
Venipuncture to collect 3 mL of whole blood into a Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion.
Report Delivery
Transport sample to lab within 4 hours. If not possible, prepare Platelet Poor Plasma (PPP) within 1 hour by centrifuging at 3600 rpm for 15 minutes, transferring supernatant, centrifuging again, and freezing immediately. Ship frozen without thawing.
Timeline: Reports are typically available the next day after sample receipt by 9 am on Thursday.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Factor II Functional Test is to evaluate the functional activity of prothrombin in the blood, aiding in the diagnosis of clotting disorders, assessing risk for thrombotic events, and guiding treatment plans for patients with coagulation abnormalities.
How to Prepare
- Collect 3 mL whole blood in Blue Top tube
- Mix by inversion immediately after collection
- Ensure sample reaches lab within 4 hours or process for PPP
- Freeze PPP if delayed, ship frozen
- Complete Coagulation Requisition Form (Form 15)
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Factor II Functional Test is essential for evaluating prothrombin activity, helping to identify risks for blood clots or bleeding disorders, especially in patients with a family history or prior clotting events."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
Understanding Your Results
Elevated Factor II activity may increase risk of blood clots, such as deep vein thrombosis or stroke. Further evaluation needed.
Level: High
Activity within reference range suggests normal clotting function. Continue monitoring if symptoms persist.
Level: Normal
Reduced activity may indicate bleeding disorders or liver dysfunction. Clinical correlation required for management.
Level: Low
Consult a doctor if you experience symptoms like unexplained swelling, pain, or redness in limbs, chest pain, shortness of breath, or if you have a family history of clotting disorders. Also, consult if test results are abnormal or if you are planning surgery or pregnancy.
Risks & Considerations
- ●Minor bruising or pain at puncture site
- ●Rare risk of infection or dizziness
Interfering Factors
- ●Heparin therapy: Discontinue for 1 day prior to sampling
- ●Oral anticoagulants: Discontinue for 7 days prior to sampling, with physician consent
- ●Recent blood transfusions or plasma products
- ●Liver disease affecting protein synthesis
Frequently Asked Questions
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