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DNA Labs India

G-6-PD Quantitative Test

DNA Labs India | ISO 9001:2015 Certified

G-6-PD Quantitative Test

Short Name: G6PD Quantitative Test

Also known as: G6PD Quantitative Assay, Glucose-6-Phosphate Dehydrogenase Test, G-6-PD Enzyme Test

G-6-PD Quantitative Test test available at DNA Labs India for ₹971. Uses Kinetic UV Assay on Whole blood samples. Results in Same day. Free home collection in 300+ cities across India.

Quantitative Enzyme Assay🏠 Home Collection

🩺 Medically Reviewed By

Overview

This assay is specifically useful for the evaluation of individuals with Coombs-negative non-spherocytic hemolytic anemia, helping to identify underlying G-6-PD deficiency as a cause. It quantifies enzyme activity to confirm diagnosis, guide treatment, and prevent complications such as acute hemolytic crises.

Test Code
629
Price
₹971
Sample Type
Whole blood
Result Time
Same day
Fasting Required
No
Method
Kinetic UV Assay
Step 1

Sample Collection

No special preparation required. Avoid strenuous exercise before sample collection to prevent hemolysis.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture will be performed by a trained phlebotomist. Ensure the sample is collected in the specified EDTA tube.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Mild bruising may occur, which is normal.

Timeline: Same day

Patient Instructions

1
Before the Test:No specific preparation is needed. Inform your doctor about any medications or recent health issues.
2
During the Test:A blood sample will be drawn from a vein in your arm. The process is quick and minimally invasive.
3
After the Test:You can resume normal activities immediately. Apply a bandage if needed.

About This Test

Who Should Get This Test

This assay is specifically useful for the evaluation of individuals with Coombs-negative non-spherocytic hemolytic anemia, helping to identify underlying G-6-PD deficiency as a cause. It quantifies enzyme activity to confirm diagnosis, guide treatment, and prevent complications such as acute hemolytic crises.

How to Prepare

  • No fasting required
  • Bring a doctor's prescription if available
  • Inform the collector about any recent blood transfusions or medications

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"G-6-PD deficiency is a common X-linked genetic disorder affecting red blood cells. Early diagnosis through quantitative testing helps in managing symptoms, avoiding triggers like certain drugs or fava beans, and monitoring treatment to prevent hemolytic episodes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume3 mL (2 mL min.)
ContainerLavender Top (EDTA) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerated: 3 weeks
Frozen: Not applicable
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Improperly labeled or stored sample

Understanding Your Results

Results are interpreted based on enzyme activity levels. Low levels indicate G-6-PD deficiency, while normal levels suggest no deficiency. Always correlate with clinical symptoms and medical history.
📊

Low G-6-PD activity

Indicates G-6-PD deficiency, which may lead to hemolytic anemia. Severity can vary based on enzyme level and triggers.

Action: Consult a physician for further evaluation and management. Avoid known triggers like fava beans and certain drugs.

📊

Normal G-6-PD activity

Suggests no significant enzyme deficiency. However, symptoms may persist due to other causes.

Action: If symptoms continue, additional tests may be recommended by your doctor.

📊

Intermediate G-6-PD activity

May indicate carrier status (especially in females) or partial deficiency. Requires clinical correlation.

Action: Discuss results with a healthcare provider for personalized advice.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like jaundice, anemia, or dark urine, or if you have a family history of G-6-PD deficiency. After a positive test result, seek medical guidance for management and trigger avoidance.

Limitations

  • May not detect all genetic variants, especially in heterozygous females
  • Cannot differentiate between specific G-6-PD variants
  • Results may be influenced by sample handling and storage conditions

Risks & Considerations

  • Minor pain or bruising at the puncture site
  • Rare risk of infection or fainting

Interfering Factors

  • Recent blood transfusion (may yield false normal results)
  • Acute hemolytic episode (can temporarily lower enzyme levels)
  • Hemolyzed sample
  • Certain medications (e.g., primaquine) that may affect enzyme stability

Compare With Similar Tests

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Frequently Asked Questions

What is G-6-PD deficiency?
G-6-PD deficiency is a genetic disorder where the glucose-6-phosphate dehydrogenase enzyme is lacking, leading to red blood cell breakdown and potential anemia.
Why is the G-6-PD Quantitative Test done?
It is done to diagnose G-6-PD deficiency, assess enzyme activity levels, and monitor treatment for the condition.
Who should get this test?
Individuals with symptoms like jaundice, anemia, dark urine, or a family history of G-6-PD deficiency should consider this test.
How is the test performed?
A blood sample is collected from a vein and analyzed using kinetic UV assay to measure enzyme activity.
Is fasting required for the G-6-PD test?
No, fasting is not required. No special preparation is needed before the test.
What is the cost of the G-6-PD Quantitative Test?
The cost in India is INR 971.1, which includes home sample collection and report generation.
How long does it take to get results?
Results are typically available the same day if the sample is collected by 4 pm.
What do low G-6-PD levels mean?
Low levels indicate G-6-PD deficiency, which can increase the risk of hemolytic anemia triggered by certain factors.
Is the test painful?
The test involves a standard blood draw, which may cause minor discomfort or bruising, but it is generally not painful.
Can females have G-6-PD deficiency?
Yes, but it is more common in males due to X-linked inheritance. Females can be carriers and may have variable enzyme levels.
What triggers hemolytic episodes in G-6-PD deficiency?
Triggers include certain drugs (e.g., antimalarials), fava beans, infections, and stress.
How can I book the test with DNA Labs India?
You can book online through the DNA Labs India website or app for free home sample collection across India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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