MPL (Myeloproliferative Leukemia) Gene Mutation Test
Short Name: MPL Gene Mutation Test
Also known as: MPL Mutation Analysis, MPL Gene Sequencing, Myeloproliferative Leukemia Gene Test
MPL (Myeloproliferative Leukemia) Gene Mutation Test test available at DNA Labs India for ₹6,500. Uses PCR, Fragment Analysis on Whole Blood samples. Results in Reports are typically available within 2 days of sample collection, with sample pickup on Monday/Thursday by 11 am and report delivery on Wednesday/Saturday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect mutations in the MPL gene for the diagnosis of myeloproliferative neoplasms and related blood disorders, aiding in clinical decision-making and treatment planning.
- Test Code
- 1257
- Price
- ₹6,500
- Sample Type
- Whole Blood
- Result Time
- Reports are typically available within 2 days of sample collection, with sample pickup on Monday/Thursday by 11 am and report delivery on Wednesday/Saturday.
- Fasting Required
- No
- Method
- PCR, Fragment Analysis
Sample Collection
Complete and submit the mandatory Genomics Clinical Information Requisition Form (Form 20). Ensure no special preparation is required unless advised by your doctor.
Method: Venipuncture
Laboratory Analysis
A standard blood draw procedure will be performed by a trained phlebotomist using an EDTA tube.
Report Delivery
Apply pressure to the puncture site to prevent bruising. The sample will be shipped refrigerated for analysis.
Timeline: Reports are typically available within 2 days of sample collection, with sample pickup on Monday/Thursday by 11 am and report delivery on Wednesday/Saturday.
Patient Instructions
About This Test
Who Should Get This Test
To detect mutations in the MPL gene for the diagnosis of myeloproliferative neoplasms and related blood disorders, aiding in clinical decision-making and treatment planning.
How to Prepare
- Use a Lavender Top (EDTA) tube
- Collect 3 mL of whole blood (minimum 2 mL)
- Ship sample refrigerated; do not freeze
- Ensure the requisition form is duly filled and accompanies the sample
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early detection of MPL mutations is crucial for diagnosing myeloproliferative neoplasms and guiding targeted therapies to improve patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Incorrect tube type or missing requisition form
- Sample stored improperly (e.g., frozen)
Understanding Your Results
Mutation Detected
Indicates a pathogenic MPL gene mutation, consistent with a myeloproliferative neoplasm. Consultation with a hematologist or geneticist is recommended for further evaluation and treatment.
Mutation Not Detected
No MPL mutation identified. This does not exclude other genetic or acquired conditions. Consider additional clinical and laboratory assessments if symptoms persist.
If you experience symptoms such as unexplained fatigue, easy bruising, enlarged spleen, or abnormal blood counts, consult a hematologist or geneticist for a comprehensive evaluation and discussion of test results.
Limitations
- ⚠Test detects only specific known mutations in the MPL gene
- ⚠Does not screen for all genetic abnormalities or other MPN-related mutations
- ⚠Requires clinical correlation and may need additional tests for comprehensive diagnosis
Risks & Considerations
- ●Minimal risk associated with blood draw, such as slight pain or bruising at the puncture site
- ●Rare chance of infection or hematoma
Interfering Factors
- ●Hemolyzed or contaminated blood sample
- ●Improper storage or transport conditions
- ●Recent blood transfusions may affect results
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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