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DNA Labs India

Histoplasma (RNA Detection) Qualitative Test

DNA Labs India | ISO 9001:2015 Certified

Histoplasma (RNA Detection) Qualitative Test

Short Name: Histoplasma RNA Qualitative

Also known as: Histoplasma capsulatum RNA PCR, Histoplasma RNA Detection

Histoplasma (RNA Detection) Qualitative Test test available at DNA Labs India for ₹6,800. Uses Real Time PCR on Fresh tissue biopsy specimens, skin biopsy, peripheral blood, respiratory secretions, tissue specimens from various body sites samples. Results in Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.. Free home collection in 300+ cities across India.

Molecular🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to qualitatively detect the presence of Histoplasma capsulatum RNA in clinical specimens, aiding in the diagnosis of histoplasmosis. It is particularly useful in cases where culture or serology is inconclusive, and for early detection in immunocompromised patients.

Test Code
6158
CPT Code
87798
ICD Code
B39.9
Price
₹6,800
Sample Type
Fresh tissue biopsy specimens, skin biopsy, peripheral blood, respiratory secretions, tissue specimens from various body sites
Result Time
Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

No special preparation required. However, patients must sign a consent document and provide relevant clinical history.

Method: Biopsy, blood draw, or respiratory secretion collection

Step 2

Laboratory Analysis

Sample collection will be performed by trained professionals. For biopsy, local anesthesia may be used. Blood sample collection is routine.

Step 3

Report Delivery

No specific aftercare required. Patients can resume normal activities immediately.

Timeline: Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.

Patient Instructions

1
Before the Test:No special preparation required. Ensure to sign consent and provide clinical history.
2
During the Test:Sample collection is quick and minimally invasive. For biopsy, local anesthesia is used.
3
After the Test:No restrictions. Resume normal activities.

About This Test

Who Should Get This Test

The purpose of this test is to qualitatively detect the presence of Histoplasma capsulatum RNA in clinical specimens, aiding in the diagnosis of histoplasmosis. It is particularly useful in cases where culture or serology is inconclusive, and for early detection in immunocompromised patients.

How to Prepare

  • Sign the consent document before sample collection
  • Provide clinical history of patient for accurate interpretation
  • Ensure sample is transported to the lab immediately

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"Histoplasmosis can mimic tuberculosis and other granulomatous diseases. Molecular detection of Histoplasma RNA is crucial for early diagnosis, especially in immunocompromised patients. This test offers high sensitivity and specificity, aiding in timely treatment."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFresh tissue biopsy specimens, skin biopsy, peripheral blood, respiratory secretions, tissue specimens from various body sites
Sample VolumeAs per specimen type
ContainerSterile container with transport medium
Collection MethodBiopsy, blood draw, or respiratory secretion collection

Sample Stability

Tissue biopsy: Stable for 24 hours at 2-8°C
Blood: Stable for 48 hours at 2-8°C
Respiratory secretions: Stable for 24 hours at 2-8°C
Sample Rejection Criteria:
  • Inadequate sample volume
  • Sample not transported in appropriate medium
  • Hemolyzed blood samples
  • Samples received after prolonged delay without proper storage

Understanding Your Results

The test detects the presence of Histoplasma capsulatum RNA. A positive result indicates active infection. A negative result suggests absence of detectable RNA, but clinical correlation is essential.
📊

Positive

Histoplasma capsulatum RNA detected. Active infection likely. Clinical correlation and further evaluation recommended.

📊

Negative

Histoplasma capsulatum RNA not detected. Infection unlikely, but if clinical suspicion remains, consider alternative testing or repeat sampling.

⚠️ When to Consult a Doctor:

Consult your physician if you experience persistent fever, cough, chest pain, or unexplained weight loss, especially if you have been exposed to bird or bat droppings or have a weakened immune system.

Limitations

  • Qualitative test does not provide quantitative load
  • Negative result does not rule out infection if sample is inadequate
  • Test should be interpreted in conjunction with clinical findings and other diagnostic tests

Risks & Considerations

  • Minimal risk of bleeding or infection at biopsy site
  • Discomfort during blood draw
  • Rare risk of pneumothorax with lung biopsy

Interfering Factors

  • Improper sample collection or storage may lead to RNA degradation
  • Contamination during collection can cause false positives
  • Inhibitors in the sample (e.g., heme) may affect PCR amplification

Compare With Similar Tests

TestHistoplasma (RNA Detection) Qualitative TestHistoplasma Antibody TestHistoplasma Urine Antigen TestFungal Culture
ComparisonHistoplasma (RNA Detection) Qualitative Test

Frequently Asked Questions

What is the cost of the Histoplasma RNA Detection test?
The cost is INR 6800 at DNA Labs India.
What sample is required for this test?
Sample types include fresh tissue biopsy, skin biopsy, peripheral blood, respiratory secretions, and tissue from various body sites.
How is the test performed?
The test uses Real Time PCR to detect Histoplasma capsulatum RNA.
When will I get the report?
Reports are available on the 4th working day. Email reports within 48 hours, phone within 36 hours.
Is fasting required before the test?
No, fasting is not required.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across major cities in India.
What does a positive result mean?
A positive result indicates the presence of Histoplasma capsulatum RNA, suggesting active infection.
What does a negative result mean?
A negative result indicates no detectable RNA, but clinical correlation is necessary.
Can this test be done on blood samples?
Yes, peripheral blood specimens are acceptable.
Is this test covered by insurance?
Insurance coverage varies; please check with your provider.
What is the CPT code for this test?
The CPT code is 87798.
Are there any risks associated with sample collection?
Risks are minimal, including slight bleeding or infection at biopsy site.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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