HLA Mixed Antibody Screen - PRA Class I II & MICA Test
Short Name: HLA Mixed Antibody Screen
Also known as: HLA Antibody Screen, PRA Test, MICA Antibody Test, Panel Reactive Antibody Test
HLA Mixed Antibody Screen - PRA Class I II & MICA Test test available at DNA Labs India for ₹12,000. Uses Luminex X-Map technology on 3 mL serum from 1 SST samples. Results in Reports are typically available within 10-12 days after sample collection.. Free home collection in 300+ cities across India.
Overview
To detect and quantify antibodies against HLA Class I, Class II, and MICA antigens, which are critical for assessing immunological risk in organ transplantation. This helps in predicting rejection likelihood and guiding donor selection and treatment strategies.
- Test Code
- 817
- Price
- ₹12,000
- Sample Type
- 3 mL serum from 1 SST
- Result Time
- Reports are typically available within 10-12 days after sample collection.
- Fasting Required
- No
- Method
- Luminex X-Map technology
Sample Collection
No special preparation required. Provide brief clinical history including transplant status and medications.
Method: Venipuncture
Laboratory Analysis
Blood sample will be collected via venipuncture from a vein in the arm.
Report Delivery
Apply gentle pressure to the puncture site with a cotton ball to stop bleeding. Avoid heavy lifting for a few hours.
Timeline: Reports are typically available within 10-12 days after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
To detect and quantify antibodies against HLA Class I, Class II, and MICA antigens, which are critical for assessing immunological risk in organ transplantation. This helps in predicting rejection likelihood and guiding donor selection and treatment strategies.
How to Prepare
- Only recipient sample required
- Provide brief clinical history
- Ship refrigerated or frozen
- Ensure proper labeling and documentation
Doctor's Notes
"This test is crucial for assessing immunological compatibility in transplant patients to minimize rejection risk. Early detection of antibodies helps in personalized treatment plans for successful outcomes."
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume (less than 1.5 mL)
- Hemolyzed, lipemic, or contaminated samples
- Incorrect sample type or container
- Improper storage or shipping conditions
- Missing clinical history or consent
Understanding Your Results
Positive PRA (Class I or Class II)
Indicates sensitization to HLA antigens, increasing risk of organ rejection. Further testing like donor-specific antibody analysis may be needed.
Negative PRA
Suggests low immunological risk, potentially favorable for transplantation.
Positive Anti-MICA Antibodies
Presence of antibodies against MICA antigens, which may contribute to rejection and require monitoring.
High PRA Percentage
Highly sensitized patients may have limited donor options and require specialized immunosuppressive protocols.
Consult a transplant specialist or immunologist if test results are positive, if considering organ transplantation, or if there are signs of transplant rejection such as decreased organ function or fever.
Limitations
- ⚠May not detect all donor-specific antibodies
- ⚠Results can vary based on testing platform and laboratory
- ⚠Not a standalone diagnostic tool; must be correlated with clinical history
- ⚠False negatives possible in low-sensitization cases
- ⚠Limited to antibody detection; does not assess cellular immunity
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection
- ●Lightheadedness or dizziness
- ●Very rare allergic reaction to antiseptic
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Recent blood transfusions within 3 months
- ●Immunosuppressive medications
- ●Improper sample storage or handling
- ●Autoimmune conditions affecting antibody levels
Compare With Similar Tests
| Test | HLA Mixed Antibody Screen - PRA Class I II & MICA Test | HLA Typing | Crossmatch Test | Donor-Specific Antibody (DSA) Test |
|---|---|---|---|---|
| Comparison | HLA Mixed Antibody Screen - PRA Class I II & MICA Test |
Frequently Asked Questions
What is the HLA Mixed Antibody Screen - PRA Class I II & MICA Test?
Why is this test important for organ transplantation?
Who should undergo this test?
How is the sample collected for this test?
What does a positive result mean?
How long does it take to get the results?
Is the test covered by insurance?
Are there any risks associated with this test?
How should I prepare for the test?
What is the difference between PRA Class I and Class II?
Can this test be done at home?
What if the test shows high antibody levels?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.