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HTRA1 Gene CARASIL NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

HTRA1 Gene CARASIL NGS Genetic Test

Short Name: CARASIL Genetic Test

Also known as: Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

HTRA1 Gene CARASIL NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Genetic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To identify mutations in the HTRA1 gene associated with CARASIL for diagnostic purposes and genetic counseling.

Test Code
5313
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling as recommended.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be collected by a trained phlebotomist using standard venipuncture techniques.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding and avoid strenuous activity.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling as recommended.
2
During the Test:A blood sample will be collected by a trained phlebotomist using standard venipuncture techniques.
3
After the Test:Apply pressure to the puncture site to stop bleeding and avoid strenuous activity.

About This Test

Who Should Get This Test

To identify mutations in the HTRA1 gene associated with CARASIL for diagnostic purposes and genetic counseling.

How to Prepare

  • Bring identification and prescription
  • Ensure sample is labeled correctly
  • Follow any specific instructions from the healthcare provider

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Genetic testing for CARASIL is crucial for accurate diagnosis and family counseling, especially in cases with a history of stroke or dementia."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Understanding Your Results

Results indicate the presence or absence of mutations in the HTRA1 gene, which are linked to CARASIL.
Positive result: Pathogenic mutation detected, consistent with CARASIL diagnosis.
Negative result: No pathogenic mutation detected, but clinical correlation is necessary.
Variant of uncertain significance: Further testing or family studies may be required.
⚠️ When to Consult a Doctor:

If you experience symptoms like recurrent strokes, dementia, or have a family history of CARASIL, consult a healthcare professional for evaluation and possible genetic testing.

Frequently Asked Questions

What is CARASIL?
CARASIL is a rare genetic disorder that affects the small blood vessels in the brain, leading to strokes, dementia, and other neurological symptoms.
What are the symptoms of CARASIL?
Symptoms include recurrent strokes, dementia, depression, migraine with aura, gait disturbance, and urinary incontinence, typically appearing in the fourth or fifth decade of life.
How is CARASIL diagnosed?
Diagnosis is based on clinical symptoms and genetic testing, such as the HTRA1 Gene CARASIL NGS Genetic Test, to identify mutations in the HTRA1 gene.
What is the HTRA1 gene?
The HTRA1 gene encodes a protein involved in regulating cell growth and differentiation; mutations in this gene are associated with CARASIL.
What does the NGS genetic test involve?
The test uses next-generation sequencing technology to analyze the HTRA1 gene for mutations from a blood or DNA sample.
What is the cost of the HTRA1 Gene CARASIL NGS Genetic Test?
The cost is INR 20,000 at DNA Labs India, with free home sample collection available across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
Who should consider this test?
Individuals with symptoms of CARASIL, a family history of the disorder, or those seeking genetic counseling for vascular diseases.
What if the test result is positive?
A positive result indicates a mutation in the HTRA1 gene, confirming CARASIL diagnosis; consult a healthcare professional for management and family planning.
Is the test covered by insurance?
Coverage depends on the insurance provider and policy; check with your insurer for details on genetic testing coverage.
How can I book the test?
You can book the test online through DNA Labs India's website or contact them via phone or WhatsApp for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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