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DNA Labs India

Immunohistochemistry Breast Cancer Panel 2 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Breast Cancer Panel 2 Test

Short Name: IHC Breast Cancer Panel 2

Also known as: IHC Breast Panel 2, Breast Cancer IHC Panel, IHC Panel for Breast Cancer

Immunohistochemistry Breast Cancer Panel 2 Test test available at DNA Labs India for ₹6,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

ImmunohistochemistryFemaleAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To assess the expression of Estrogen Receptor (ER), Progesterone Receptor (PR), and Cathepsin D in breast cancer tissue. This helps in determining the prognosis and predicting response to endocrine therapy, which is vital for treatment planning.

Test Code
903
Price
₹6,000
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Reports typically available within 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Ensure biopsy is performed by a healthcare professional and tissue is immediately fixed in formalin.

Method: Biopsy procedure

Step 2

Laboratory Analysis

Biopsy sample is collected and placed in appropriate container.

Step 3

Report Delivery

Label the sample with patient details and send to the laboratory at room temperature.

Timeline: Reports typically available within 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:Consult with your oncologist, provide necessary medical reports, and ensure biopsy is scheduled.
2
During the Test:The biopsy procedure is performed, and tissue sample is collected for analysis.
3
After the Test:Wait for the report, which will be delivered in 5-7 days. Discuss results with your doctor.

About This Test

Who Should Get This Test

To assess the expression of Estrogen Receptor (ER), Progesterone Receptor (PR), and Cathepsin D in breast cancer tissue. This helps in determining the prognosis and predicting response to endocrine therapy, which is vital for treatment planning.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the Histopathology report, Clinical history & indicate site of biopsy.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is essential for breast cancer prognosis and treatment planning, assessing key biomarkers like ER, PR, and Cathepsin D to guide personalized therapy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Sample VolumeAs required for biopsy analysis
ContainerFormalin container or paraffin block
Collection MethodBiopsy procedure

Sample Stability

Room Temperature
Sample Rejection Criteria:
  • Sample not fixed in formalin
  • Insufficient tissue
  • Missing clinical information
  • Contaminated sample

Understanding Your Results

Results from the Immunohistochemistry Breast Cancer Panel 2 Test provide critical information for breast cancer management. Positive ER and PR indicate sensitivity to hormone therapy, while negative suggests resistance. Cathepsin D positivity may signal aggressive tumor behavior.
📊

ER Positive, PR Positive

Likely responsive to endocrine therapy such as tamoxifen.

📊

ER Negative, PR Negative

Less likely to benefit from endocrine therapy; consider chemotherapy.

📊

Cathepsin D Positive

Poor prognostic indicator; may require aggressive treatment.

📊

Malignant Cells Present

Confirms diagnosis of breast cancer.

⚠️ When to Consult a Doctor:

If you experience any symptoms of breast cancer or have been diagnosed, consult an oncologist for appropriate testing and treatment.

Limitations

  • Depends on quality of biopsy sample
  • Not a standalone diagnostic; used in conjunction with other tests
  • May not detect all subtypes of breast cancer
  • Results require interpretation by a qualified pathologist

Risks & Considerations

  • Minor bleeding at biopsy site
  • Infection risk from biopsy procedure
  • Discomfort during biopsy

Interfering Factors

  • Improper tissue fixation
  • Delay in sample processing
  • Inadequate tissue sample
  • Technical errors in immunohistochemistry staining

Compare With Similar Tests

TestImmunohistochemistry Breast Cancer Panel 2 Test
ComparisonImmunohistochemistry Breast Cancer Panel 2 Test

Frequently Asked Questions

What is the Immunohistochemistry Breast Cancer Panel 2 Test?
It is a diagnostic test that uses antibodies to detect specific proteins like ER, PR, and Cathepsin D in breast tissue to help diagnose and plan treatment for breast cancer.
Why is this test performed?
To determine the presence and type of breast cancer, assess prognosis, and guide treatment decisions, especially for hormone therapy.
What does the test measure?
It measures the expression of Estrogen Receptor (ER), Progesterone Receptor (PR), Cathepsin D, and includes a pathologist review for malignant cells.
How is the sample collected?
A biopsy sample of breast tissue is collected during a biopsy procedure and submitted in formalin or as a paraffin block.
Is fasting required for this test?
No, fasting is not required. However, you need to provide a histopathology report, clinical history, and biopsy site information.
How long does it take to get results?
Results are typically available within 5-7 days after the sample is received by the laboratory.
What is the cost of the test?
The cost is INR 6000.0, which includes home collection in many cities across India.
Is home collection available?
Yes, free home sample collection is available for online bookings in numerous cities in India.
What do positive ER and PR results mean?
Positive ER and PR indicate that the cancer may respond well to endocrine therapies like tamoxifen.
What does Cathepsin D positivity indicate?
Cathepsin D positivity is generally a poor prognostic sign, suggesting a more aggressive tumor.
How should I prepare for the test?
Ensure your biopsy is scheduled, and prepare to provide clinical reports. No special preparation is needed from the patient side.
Can this test diagnose breast cancer on its own?
No, it is part of a comprehensive diagnostic process. Results are used in conjunction with other tests and clinical evaluation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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