Immunohistochemistry HHV-8 Test
Short Name: IHC HHV-8 Test
Also known as: HHV-8 Immunohistochemistry, IHC for Human Herpesvirus 8
Immunohistochemistry HHV-8 Test test available at DNA Labs India for ₹4,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Report available in 5-7 days after sample receipt, with sample collection daily by 6 PM.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the Immunohistochemistry HHV-8 Test is to detect HHV-8 antigens in tissue samples for the diagnosis of Kaposi's sarcoma and related conditions. This test aids in confirming HHV-8 infection, which is essential for distinguishing these diseases from other malignancies and guiding appropriate treatment strategies, such as antiviral therapy or chemotherapy.
- Test Code
- 1003
- Price
- ₹4,000
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Report available in 5-7 days after sample receipt, with sample collection daily by 6 PM.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history to ensure accurate testing.
Method: Biopsy collection
Laboratory Analysis
Tissue biopsy is performed by a qualified healthcare professional, typically from the suspected lesion or tumor.
Report Delivery
The tissue sample is preserved in 10% Formal-saline or Formalin fixed paraffin embedded block for laboratory processing.
Timeline: Report available in 5-7 days after sample receipt, with sample collection daily by 6 PM.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Immunohistochemistry HHV-8 Test is to detect HHV-8 antigens in tissue samples for the diagnosis of Kaposi's sarcoma and related conditions. This test aids in confirming HHV-8 infection, which is essential for distinguishing these diseases from other malignancies and guiding appropriate treatment strategies, such as antiviral therapy or chemotherapy.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature to maintain sample integrity
- Include a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for confirming HHV-8 presence in suspected Kaposi's sarcoma cases, aiding in accurate diagnosis and treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate or improperly preserved tissue sample
- Missing clinical history or biopsy site information
- Sample contamination or insufficient tissue quantity
Understanding Your Results
Positive
HHV-8 antigens are detected, suggesting HHV-8 infection. This is consistent with conditions like Kaposi's sarcoma and requires further clinical evaluation for treatment.
Negative
No HHV-8 antigens are detected. However, a negative result does not rule out infection if clinical suspicion remains high; additional testing may be recommended.
Consult a doctor if you experience symptoms such as red or purple skin patches, unexplained lumps, swelling in legs, shortness of breath, or coughing up blood, especially if you are HIV-positive or have a weakened immune system.
Limitations
- ⚠Cannot quantify viral load or detect active replication
- ⚠Requires tissue biopsy, not a blood-based test
- ⚠May yield false negatives if antigen expression is low or patchy
- ⚠Results must be correlated with clinical and histopathological findings
Risks & Considerations
- ●Minimal risks associated with biopsy procedure, such as bleeding or infection at the collection site
- ●No risks from the immunohistochemistry test itself, as it is performed on collected samples
Interfering Factors
- ●Improper tissue fixation or preservation
- ●Sample degradation during transport
- ●Technical errors in immunohistochemical staining
- ●Insufficient tissue for analysis
Compare With Similar Tests
| Test | Immunohistochemistry HHV-8 Test | |||
|---|---|---|---|---|
| Comparison | Immunohistochemistry HHV-8 Test |
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