Immunohistochemistry HMB-45 Test
Short Name: HMB-45 IHC Test
Also known as: HMB-45 Immunohistochemistry, Melanoma Marker Test
Immunohistochemistry HMB-45 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Report available in 5-7 days, with sample processing daily by 6 pm.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect the presence of melanoma by identifying HMB-45 protein in tissue samples, aiding in accurate diagnosis and treatment planning.
- Test Code
- 944
- Price
- ₹3,000
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Report available in 5-7 days, with sample processing daily by 6 pm.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Consult a specialist and provide necessary documentation, including histopathology report, site of biopsy, and clinical history.
Method: Tissue biopsy
Laboratory Analysis
A tissue biopsy is performed by a healthcare professional from the suspected area.
Report Delivery
The sample is preserved and sent to the laboratory for immunohistochemistry analysis.
Timeline: Report available in 5-7 days, with sample processing daily by 6 pm.
Patient Instructions
About This Test
Who Should Get This Test
To detect the presence of melanoma by identifying HMB-45 protein in tissue samples, aiding in accurate diagnosis and treatment planning.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
- Ship at room temperature.
- Provide a copy of the Histopathology report, Site of biopsy, and Clinical history.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is a gold standard for confirming melanoma, aiding in timely treatment planning and improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample without clinical history or biopsy site information
- Improperly fixed or damaged tissue
- Inadequate sample size
Understanding Your Results
If you have symptoms of melanoma, such as changes in moles, or if your test results are abnormal or inconclusive.
Limitations
- ⚠Cannot be used for population screening
- ⚠Requires correlation with clinical and histopathological findings
- ⚠May yield false positives in some non-melanoma conditions
- ⚠Dependent on sample quality and pathologist expertise
Risks & Considerations
- ●Minor bleeding or discomfort at biopsy site
- ●Risk of infection
- ●Scarring
- ●False results requiring further testing
Interfering Factors
- ●Poor tissue fixation
- ●Inadequate sample size
- ●Technical errors in staining
- ●Contamination during processing
Compare With Similar Tests
| Test | Immunohistochemistry HMB-45 Test | S-100 Immunohistochemistry | Melan-A (MART-1) Test | SOX10 Stain | Skin Biopsy with Histopathology |
|---|---|---|---|---|---|
| Comparison | Immunohistochemistry HMB-45 Test |
Frequently Asked Questions
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