Immunohistochemistry P16 Test
Also known as: p16INK4a Immunohistochemistry Test, P16 IHC Test
Immunohistochemistry P16 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To detect p16INK4a protein overexpression in tissue samples for diagnosing HPV-related cancers, including cervical and oropharyngeal carcinomas.
- Test Code
- 1021
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports are typically available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Method: Biopsy
Laboratory Analysis
Tissue sample is collected via biopsy from the cervix or affected area.
Report Delivery
Sample is processed and examined in the laboratory using immunohistochemistry methods.
Timeline: Reports are typically available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To detect p16INK4a protein overexpression in tissue samples for diagnosing HPV-related cancers, including cervical and oropharyngeal carcinomas.
How to Prepare
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
- Ship at room temperature.
- Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is crucial for diagnosing HPV-related cervical cancer and guiding treatment decisions, especially in early stages."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate or insufficient sample
- Improper fixation or storage
- Missing clinical information or reports
Understanding Your Results
Positive p16 expression
Indicates HPV infection and increased risk of cervical cancer or related lesions. May require further evaluation and treatment.
Negative p16 expression
Suggests no significant HPV infection or abnormal cells in the tissue. Indicates lower risk but clinical follow-up may be advised.
If you experience symptoms such as abnormal vaginal bleeding, pelvic pain, or unusual discharge, consult an oncologist or gynecologist for evaluation.
Limitations
- ⚠May show expression in some non-HPV related tumors
- ⚠Not solely diagnostic; clinical correlation and additional tests may be needed
Risks & Considerations
- ●Minimal risks associated with biopsy, such as infection, bleeding, or discomfort
Frequently Asked Questions
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