INSR Gene Diabetes mellitus, insulin-resistant with acanthosis nigricans NGS Genetic Test
Short Name: INSR Gene Diabetes NGS Test
Also known as: INSR Gene Test, Insulin Resistance Genetic Test, Acanthosis Nigricans Genetic Test
INSR Gene Diabetes mellitus, insulin-resistant with acanthosis nigricans NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the INSR gene associated with insulin-resistant diabetes mellitus and acanthosis nigricans, aiding in diagnosis, genetic counseling, and personalized treatment planning.
- Test Code
- 4665
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample receipt
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No specific preparation required. Provide detailed clinical history and family pedigree during genetic counseling.
Method: Venipuncture or FTA card spotting
Laboratory Analysis
A blood sample will be drawn by a trained phlebotomist using sterile techniques, or a drop of blood will be applied to an FTA card.
Report Delivery
Apply pressure to the puncture site with a cotton ball to stop bleeding. Keep the area clean and dry.
Timeline: 3 to 4 weeks from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the INSR gene associated with insulin-resistant diabetes mellitus and acanthosis nigricans, aiding in diagnosis, genetic counseling, and personalized treatment planning.
How to Prepare
- Ensure proper patient identification and labeling of samples
- Use sterile equipment and follow aseptic techniques
- For FTA cards, allow blood to dry completely before packaging
- Transport samples at ambient room temperature unless specified otherwise
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for diagnosing genetic forms of insulin resistance, guiding personalized treatment, and informing family risk assessment for diabetes mellitus."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed, clotted, or insufficient sample volume
- Improper labeling or mismatched patient information
- Contaminated or degraded samples
- Samples not collected according to instructions
Understanding Your Results
Positive for pathogenic mutation
Increased risk of insulin-resistant diabetes mellitus and acanthosis nigricans; genetic counseling and clinical correlation recommended.
Negative for mutations
No pathogenic variants detected in the INSR gene; other genetic or environmental factors may be involved.
Variant of uncertain significance (VUS)
Genetic variant identified but clinical significance is unknown; further testing and family studies may be needed.
Likely pathogenic variant
Strong evidence for association with disease; similar management as pathogenic variants may be considered.
If you experience symptoms of diabetes mellitus such as increased thirst, frequent urination, or fatigue, or if you have a family history of insulin resistance or acanthosis nigricans, consult a healthcare professional for evaluation and possible genetic testing.
Limitations
- ⚠Only detects mutations in the INSR gene; may not identify all genetic causes of insulin resistance
- ⚠Results require interpretation by a geneticist or healthcare professional
- ⚠Cannot predict disease onset or severity with certainty
- ⚠May not detect large deletions or duplications without additional methods
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results, including anxiety or stress
- ●Potential for uncertain results requiring further investigation
Interfering Factors
- ●Sample degradation or contamination
- ●Insufficient DNA quantity or quality
- ●Hemolyzed or lipemic blood samples
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | INSR Gene Diabetes mellitus, insulin-resistant with acanthosis nigricans NGS Genetic Test | ||||
|---|---|---|---|---|---|
| Comparison | INSR Gene Diabetes mellitus, insulin-resistant with acanthosis nigricans NGS Genetic Test | Measures current blood sugar levels but does not identify genetic causes. | Targeted but less comprehensive than NGS for detecting multiple variants. | Broader genetic analysis but more expensive and may yield incidental findings. | Physical assessment that can indicate insulin resistance but not genetic etiology. |
Frequently Asked Questions
What is the INSR gene?
What is insulin-resistant diabetes mellitus?
What are the symptoms of INSR gene diabetes?
How is the NGS genetic test performed?
What sample is required for the test?
How long does it take to get results?
What is the cost of the INSR gene test?
Is home sample collection available?
What do the results mean?
Can this test diagnose all types of diabetes?
Is genetic counseling recommended before testing?
How accurate is the NGS genetic test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.