Skip to main content
DNA Labs India

JAM3 Gene Hemorrhagic destruction of the brain, subependymal calcification, and cataracts NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

JAM3 Gene Hemorrhagic destruction of the brain, subependymal calcification, and cataracts NGS Genetic Test

Short Name: JAM3 Gene NGS Test

Also known as: JAM3 Gene Test, Hemorrhagic Brain Destruction Genetic Test

JAM3 Gene Hemorrhagic destruction of the brain, subependymal calcification, and cataracts NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect genetic mutations in the JAM3 gene associated with hemorrhagic destruction of the brain, subependymal calcification, and cataracts for accurate diagnosis and management.

Test Code
5324
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history and genetic counseling session recommended to draw a pedigree chart of family members.

Method: Venipuncture or Blood drop on FTA card

Step 2

Laboratory Analysis

Blood sample collection via venipuncture or one drop on FTA card as per instructions.

Step 3

Report Delivery

Sample is sent to the laboratory for NGS analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and informed consent are required before sample collection.
2
During the Test:Sample collection is performed as per standard protocols with minimal discomfort.
3
After the Test:Results are available online or via email/WhatsApp within 3 to 4 weeks.

About This Test

Who Should Get This Test

To detect genetic mutations in the JAM3 gene associated with hemorrhagic destruction of the brain, subependymal calcification, and cataracts for accurate diagnosis and management.

How to Prepare

  • Ensure proper sample handling and labeling
  • Use sterile equipment for blood collection

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for early diagnosis and management of rare genetic conditions affecting the brain and eyes, aiding in informed clinical decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or Blood drop on FTA card

Sample Stability

Blood: stable at room temperature for 24 hours
FTA card: stable for extended periods at room temperature
Sample Rejection Criteria:
  • Hemolyzed or insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the JAM3 gene, guiding clinical diagnosis and management.
Positive: Pathogenic variant detected, associated with the condition
Negative: No pathogenic variants detected
Variant of uncertain significance: Further testing or clinical correlation may be needed
⚠️ When to Consult a Doctor:

If symptoms persist, family history is positive, or results are abnormal, consult a geneticist, neurologist, or ophthalmologist.

Limitations

  • ⚠Test may not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Potential psychological impact of genetic results

Interfering Factors

  • ●None known

Frequently Asked Questions

What is the JAM3 Gene NGS Genetic Test?
It is a genetic test using NGS technology to detect mutations in the JAM3 gene associated with hemorrhagic brain destruction, subependymal calcification, and cataracts.
What conditions does this test diagnose?
It diagnoses a rare vascular disorder caused by JAM3 gene mutations, leading to brain hemorrhage, calcification, and cataracts.
What are the symptoms of JAM3 gene mutations?
Symptoms include headaches, vomiting, seizures, visual disturbances, developmental delays, and cataracts.
How is the test performed?
The test involves analyzing DNA from a blood sample or extracted DNA using Next-Generation Sequencing (NGS) technology.
What sample is required for the test?
A blood sample, extracted DNA, or one drop of blood on an FTA card is required.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What is the cost of the test?
The test costs INR 20,000, which includes testing, analysis, and a detailed report.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
What cities do you offer home collection in?
Home collection is available in numerous cities including Mumbai, Delhi, Bangalore, Hyderabad, and many more across India.
Do I need genetic counseling before the test?
Yes, a genetic counseling session is recommended to draw a pedigree chart and understand the test implications.
What does a positive result mean?
A positive result indicates the presence of a pathogenic variant in the JAM3 gene, associated with the condition, and requires clinical management.
Is the test covered by insurance?
Coverage depends on your insurance provider; check with them for details. Government schemes like PMJAY may not cover it.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

MMC (Maternal Myopathy with Cardiomyopathy) Mutation Detection Test

₹11,500

LPA Gene Coronary artery disease, susceptibility to NGS Genetic Test

₹20,000

ITIH4 Gene Hypercholesterolemia, susceptibility to NGS Genetic Test

₹20,000

PPP1R17 Gene Hypercholesterolemia, susceptibility to NGS Genetic Test

₹20,000

APOA1 Gene Hypoalphalipoproteinemia NGS Genetic Test

₹20,000

GJC2 Gene Lymphedema, hereditary, type IC NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.