JC/BK (DNA Detection) (RNA Detection) Qualitative Test
Short Name: JC/BK Qualitative
Also known as: JC Virus PCR, BK Virus PCR, Polyomavirus PCR, JC/BK Viral Detection
JC/BK (DNA Detection) (RNA Detection) Qualitative Test test available at DNA Labs India for ₹5,780. Uses Real Time PCR on Whole blood, urine, serum, CSF, Biopsies samples. Results in Reports are available on the 3rd working day after sample collection. Email reports are sent within 36 hours of result availability, and phone consultation is available within 24 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the JC/BK (DNA Detection) (RNA Detection) Qualitative Test is to detect the presence of JC or BK virus DNA in a patient's sample. This aids in diagnosing active infections, especially in immunocompromised individuals. Early detection of JCV is critical for preventing PML, while BKV detection helps in managing renal transplant complications. The test also assists in monitoring viral load changes over time, evaluating response to antiviral therapy, and screening high-risk patients before and after transplantation.
- Test Code
- 6172
- CPT Code
- 87799
- ICD Code
- B34.4
- Price
- ₹5,780
- Sample Type
- Whole blood, urine, serum, CSF, Biopsies
- Result Time
- Reports are available on the 3rd working day after sample collection. Email reports are sent within 36 hours of result availability, and phone consultation is available within 24 hours.
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
No special preparation is required. However, patients must sign a consent document and provide relevant clinical history. Inform your healthcare provider about any medications you are taking, especially immunosuppressants.
Method: Venipuncture, urine collection, lumbar puncture, biopsy
Laboratory Analysis
Blood sample is drawn from a vein in the arm. Urine sample is collected in a sterile container. CSF collection is performed by a healthcare professional via lumbar puncture. Biopsy samples are collected during a surgical procedure.
Report Delivery
No specific aftercare is needed. You can resume normal activities immediately. For CSF collection, follow your doctor's instructions regarding rest and hydration.
Timeline: Reports are available on the 3rd working day after sample collection. Email reports are sent within 36 hours of result availability, and phone consultation is available within 24 hours.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the JC/BK (DNA Detection) (RNA Detection) Qualitative Test is to detect the presence of JC or BK virus DNA in a patient's sample. This aids in diagnosing active infections, especially in immunocompromised individuals. Early detection of JCV is critical for preventing PML, while BKV detection helps in managing renal transplant complications. The test also assists in monitoring viral load changes over time, evaluating response to antiviral therapy, and screening high-risk patients before and after transplantation.
How to Prepare
- Ensure the sample is collected in the appropriate container as specified
- For urine, use a sterile container and collect midstream urine
- For blood, use an EDTA tube and mix gently
- Label the sample with patient's name, date, and time of collection
- Transport the sample to the laboratory as soon as possible
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"JC/BK virus reactivation is a significant concern in immunocompromised patients. Early detection through qualitative PCR helps guide antiviral therapy and monitoring."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Urine sample with excessive contamination
- Improperly labeled sample
- Sample received after prolonged delay without proper storage
- Insufficient sample volume
Understanding Your Results
JC Virus Detected
Indicates active JC virus infection. In immunocompromised patients, this may suggest PML. Clinical correlation and further evaluation (e.g., MRI brain) are recommended.
BK Virus Detected
Indicates active BK virus infection. In renal transplant patients, this may indicate BK virus nephropathy. Monitoring of renal function and antiviral therapy may be required.
Both Viruses Not Detected
No evidence of active JC or BK virus infection. However, if symptoms persist, consider repeat testing or alternative diagnoses.
Consult your healthcare provider if you have a positive result or if you experience symptoms such as persistent fever, neurological deficits, or urinary symptoms. Early intervention is crucial in immunocompromised patients.
Limitations
- ⚠Qualitative test does not provide viral load quantification; quantitative testing may be needed for monitoring
- ⚠False negatives possible if viral load is below the assay's limit of detection
- ⚠Positive result does not differentiate between latent and active infection; clinical correlation required
- ⚠Test should be interpreted in conjunction with clinical findings and other laboratory tests
Risks & Considerations
- ●Blood draw: minor bruising, bleeding, or infection at puncture site
- ●Urine collection: no risk
- ●CSF collection: headache, infection, bleeding, or nerve damage (rare)
- ●Biopsy: bleeding, infection, or organ damage (rare)
Interfering Factors
- ●Sample contamination with non-target DNA
- ●Inhibitors in the sample (e.g., hemoglobin, heparin, urine crystals)
- ●Improper sample collection or storage leading to DNA degradation
- ●Cross-reactivity with other polyomaviruses (rare)
- ●Low viral load below the detection limit of the assay
Compare With Similar Tests
| Test | JC/BK (DNA Detection) (RNA Detection) Qualitative Test | JC/BK Quantitative PCR | Antibody Serology (IgG/IgM) | Viral Culture |
|---|---|---|---|---|
| Comparison | JC/BK (DNA Detection) (RNA Detection) Qualitative Test |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
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