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LPIN2 Gene Majeed syndrome NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

LPIN2 Gene Majeed syndrome NGS Genetic Test

Short Name: LPIN2 Gene Majeed Syndrome Test

Also known as: Majeed Syndrome Genetic Test, LPIN2 Mutation Analysis

LPIN2 Gene Majeed syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect mutations in the LPIN2 gene for accurate diagnosis of Majeed syndrome, aiding in clinical management and genetic counseling.

Test Code
2428
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Clinical history review and genetic counseling session recommended to draw a pedigree chart.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or FTA card under sterile conditions.

Step 3

Report Delivery

Sample labeled and transported to the laboratory for DNA extraction and analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and informed consent are required. Provide detailed clinical and family history.
2
During the Test:Sample undergoes DNA extraction and next-generation sequencing for LPIN2 gene analysis.
3
After the Test:Report generated with interpretation; genetic counseling recommended for result discussion.

About This Test

Who Should Get This Test

To detect mutations in the LPIN2 gene for accurate diagnosis of Majeed syndrome, aiding in clinical management and genetic counseling.

How to Prepare

  • Ensure proper patient identification and sample labeling
  • Avoid hemolysis during blood draw
  • Use FTA card for one-drop blood collection if applicable

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for Majeed syndrome can guide treatment and management, especially for family planning and symptom control."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required
ContainerFTA Card or EDTA Tube
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood: Store at 2-8°C for up to 24 hours
FTA Card: Stable at room temperature for extended periods
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated or hemolyzed sample
  • Incorrect sample type

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the LPIN2 gene, which are associated with Majeed syndrome.
📊

Pathogenic variant detected

Consistent with Majeed syndrome diagnosis; clinical correlation and genetic counseling advised.

📊

No pathogenic variant detected

Majeed syndrome unlikely; consider other differential diagnoses and further clinical evaluation.

⚠️ When to Consult a Doctor:

If symptoms of Majeed syndrome are present, for family planning with a history of the disorder, or to discuss test results and treatment options.

Limitations

  • ⚠May not detect all rare or novel mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risk from blood draw (e.g., bruising, infection)
  • ●Psychological impact of genetic results; counseling available

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample handling

Compare With Similar Tests

TestLPIN2 Gene Majeed syndrome NGS Genetic Test
ComparisonLPIN2 Gene Majeed syndrome NGS Genetic Test

Frequently Asked Questions

What is Majeed syndrome?
Majeed syndrome is a rare genetic disorder caused by LPIN2 gene mutations, leading to recurrent fever, bone inflammation, skin lesions, and anemia.
What causes Majeed syndrome?
It is caused by mutations in the LPIN2 gene, which reduces lipin-2 enzyme activity, affecting fat metabolism and immune function.
What are the common symptoms of Majeed syndrome?
Symptoms include recurrent fever, bone and joint pain, red skin lesions on palms and soles, growth retardation, osteoporosis, and anemia.
How is Majeed syndrome diagnosed?
Diagnosis involves clinical evaluation, blood tests for inflammation markers, and genetic testing to confirm LPIN2 gene mutations.
What is the LPIN2 gene NGS test?
It is a next-generation sequencing test that analyzes the entire LPIN2 gene to detect mutations associated with Majeed syndrome.
How much does the LPIN2 gene test cost in India?
The cost is approximately INR 20,000 at DNA Labs India, with free home sample collection available.
Is the test covered by insurance?
Coverage varies; check with your insurance provider. Some plans may cover genetic testing for diagnostic purposes.
How long does it take to get test results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection across many cities in India for online bookings.
What should I do before taking the test?
Provide clinical history, undergo genetic counseling, and ensure informed consent. No fasting is required.
Can the test detect all mutations in the LPIN2 gene?
NGS is highly sensitive, but it may not detect all rare or novel mutations. Genetic counseling is recommended for interpretation.
What are the treatment options for Majeed syndrome?
Treatment focuses on symptom management, such as anti-inflammatory drugs for pain and fever, and supportive care for anemia and growth issues.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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