Lyme Disease (Borrelia Burgdorferi) IgG Immunoblot Test
Short Name: Lyme IgG Immunoblot
Also known as: Lyme Disease Antibody Test, Borrelia IgG Immunoblot, Lyme Serology
Lyme Disease (Borrelia Burgdorferi) IgG Immunoblot Test test available at DNA Labs India for ₹13,000. Uses Immunoblot on Serum samples. Results in Reports are available after 2-3 weeks from sample submission.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the IgG immunoblot test is to confirm a diagnosis of Lyme disease by detecting specific IgG antibodies to Borrelia burgdorferi. It is used as a follow-up test after initial positive results from screening methods like ELISA or IFA, providing high specificity to reduce false positives.
- Test Code
- 1196
- Price
- ₹13,000
- Sample Type
- Serum
- Result Time
- Reports are available after 2-3 weeks from sample submission.
- Fasting Required
- No
- Method
- Immunoblot
Sample Collection
Ensure a duly filled Test Send Out Consent Form (Form 35) is mandatory. No fasting required.
Method: Venipuncture
Laboratory Analysis
Standard venipuncture procedure to collect 2 mL of blood in a serum separator tube (SST).
Report Delivery
Apply pressure to the puncture site to prevent bruising. Store sample appropriately as per stability guidelines.
Timeline: Reports are available after 2-3 weeks from sample submission.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the IgG immunoblot test is to confirm a diagnosis of Lyme disease by detecting specific IgG antibodies to Borrelia burgdorferi. It is used as a follow-up test after initial positive results from screening methods like ELISA or IFA, providing high specificity to reduce false positives.
How to Prepare
- Collect 2 mL of blood in an SST tube.
- Label the sample correctly with patient details.
- Ship refrigerated or frozen as specified.
- Include the mandatory Test Send Out Consent Form (Form 35).
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Early diagnosis of Lyme disease is crucial for effective treatment. The IgG immunoblot test is a confirmatory method that helps detect past exposure to Borrelia burgdorferi, guiding appropriate medical management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or lipemic serum
- Missing consent form
- Improper labeling or storage
Understanding Your Results
Positive
Detectable IgG antibodies to Borrelia burgdorferi, indicating past exposure or infection. Consult a healthcare provider for further evaluation.
Negative
No detectable IgG antibodies. If symptoms persist, consider repeat testing or alternative diagnoses.
Equivocal
Indeterminate results; repeat testing or additional clinical assessment recommended.
Consult a doctor if you have symptoms of Lyme disease, such as fever, rash, or joint pain, especially after a tick bite. Also, seek medical advice after a positive test result for appropriate management.
Limitations
- ⚠May not detect early-stage Lyme disease before antibodies develop
- ⚠Cannot distinguish between active and past infection
- ⚠Results should be interpreted in clinical context
- ⚠Not suitable for initial screening
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection or dizziness
Interfering Factors
- ●Cross-reactivity with other infections
- ●Previous vaccination or antibiotic treatment
- ●Immunosuppressive conditions
- ●Hemolyzed or lipemic samples
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Frequently Asked Questions
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