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DNA Labs India

M. Leprosy (RNA Detection) Qualitative Test

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M. Leprosy (RNA Detection) Qualitative Test

Short Name: M. Leprosy RNA Qualitative

Also known as: Leprosy RNA PCR, Mycobacterium leprae RNA detection, Hansen's disease RNA test

M. Leprosy (RNA Detection) Qualitative Test test available at DNA Labs India for ₹4,760. Uses Real-Time PCR (RT-PCR) on Ear droppings, Lesion curatings, Biopsy of patches, Scrapings of nasal mucosa, Urine samples. Results in Reports are delivered on the 3rd working day. Email reports are sent within 36 hours of result availability, and phone support is available 24 hours.. Free home collection in 300+ cities across India.

Molecular🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to qualitatively detect the presence of Mycobacterium leprae RNA in clinical specimens, aiding in the early and accurate diagnosis of leprosy. It is particularly useful for confirming infection in suspected cases, especially when clinical signs are inconclusive or when early detection is critical for preventing disability.

Test Code
6179
CPT Code
87798
ICD Code
A30.9
Price
₹4,760
Sample Type
Ear droppings, Lesion curatings, Biopsy of patches, Scrapings of nasal mucosa, Urine
Result Time
Reports are delivered on the 3rd working day. Email reports are sent within 36 hours of result availability, and phone support is available 24 hours.
Fasting Required
No
Method
Real-Time PCR (RT-PCR)
Step 1

Sample Collection

No special preparation is required. However, patients must sign a consent document and provide relevant clinical history.

Method: Swab, biopsy, or scraping by trained professional

Step 2

Laboratory Analysis

Sample collection is performed by a trained professional using sterile techniques. The procedure is quick and minimally invasive.

Step 3

Report Delivery

The sample is immediately transported to the laboratory. Patients can resume normal activities immediately after collection.

Timeline: Reports are delivered on the 3rd working day. Email reports are sent within 36 hours of result availability, and phone support is available 24 hours.

Patient Instructions

1
Before the Test:No special preparation is required. Please sign the consent document and provide your clinical history.
2
During the Test:A healthcare professional will collect the required sample (e.g., ear droppings, lesion curatings, biopsy, nasal scraping, or urine). The procedure is quick and minimally invasive.
3
After the Test:You can resume normal activities immediately. The sample will be sent to the laboratory for analysis. Results will be available on the 3rd working day.

About This Test

Who Should Get This Test

The purpose of this test is to qualitatively detect the presence of Mycobacterium leprae RNA in clinical specimens, aiding in the early and accurate diagnosis of leprosy. It is particularly useful for confirming infection in suspected cases, especially when clinical signs are inconclusive or when early detection is critical for preventing disability.

How to Prepare

  • Sign the consent document before sample collection.
  • Provide any clinical history of the patient to the lab.
  • Ensure the sample is collected in a sterile container with appropriate transport medium.
  • Sample should be shipped immediately to the laboratory.

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"Early detection of leprosy is critical to prevent disability and transmission. This RNA-based test offers high sensitivity, enabling prompt treatment initiation."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeEar droppings, Lesion curatings, Biopsy of patches, Scrapings of nasal mucosa, Urine
Sample VolumeAs required for the specific sample type
ContainerSterile container with transport medium
Collection MethodSwab, biopsy, or scraping by trained professional

Sample Stability

Sample should be processed within 24 hours if stored at 2-8°C.
For longer storage, freeze at -20°C or lower.
Avoid repeated freeze-thaw cycles.
Sample Rejection Criteria:
  • Insufficient sample volume
  • Sample not in appropriate transport medium
  • Sample contaminated or leaking
  • Sample not labeled correctly
  • Sample received after prolonged delay without proper storage

Understanding Your Results

The test result is reported as 'Detected' or 'Not Detected' for Mycobacterium leprae RNA. A 'Detected' result indicates the presence of M. leprae RNA, supporting a diagnosis of leprosy. A 'Not Detected' result suggests the absence of detectable RNA, but does not exclude infection, especially in early or paucibacillary cases.
📊

Detected

Positive for Mycobacterium leprae RNA. Consistent with active leprosy infection. Clinical correlation and treatment initiation are recommended.

📊

Not Detected

Negative for Mycobacterium leprae RNA. No evidence of infection in the tested sample. However, if clinical suspicion remains high, further testing or repeat testing may be considered.

⚠️ When to Consult a Doctor:

If you experience any symptoms suggestive of leprosy, such as skin lesions with reduced sensation, numbness, or muscle weakness, consult a physician immediately. Early diagnosis and treatment are crucial to prevent complications.

Limitations

  • A negative result does not completely rule out leprosy; clinical correlation is essential.
  • Test detects RNA, which may degrade if sample is not processed promptly.
  • Qualitative test does not quantify bacterial load.
  • Results should be interpreted by a qualified physician.

Risks & Considerations

  • Minimal risk of bleeding or infection at the sample collection site
  • Slight discomfort during biopsy or scraping
  • Rare chance of fainting during collection

Interfering Factors

  • Improper sample collection or handling
  • Insufficient sample volume
  • Contamination during collection
  • Inhibitors in the sample (e.g., blood, mucus)
  • Prior antibiotic treatment may reduce RNA levels

Compare With Similar Tests

TestM. Leprosy (RNA Detection) Qualitative TestSlit Skin Smear (SSS)M. Leprosy PCR (DNA)M. Leprosy RNA Detection (This Test)
ComparisonM. Leprosy (RNA Detection) Qualitative Test

Frequently Asked Questions

What is the M. Leprosy (RNA Detection) Qualitative Test?
It is a molecular test that detects the presence of Mycobacterium leprae RNA in clinical samples using real-time PCR, aiding in early diagnosis of leprosy.
How much does the test cost at DNA Labs India?
The test costs INR 4760, which includes free home sample collection across many cities in India.
What sample types are accepted for this test?
Ear droppings, lesion curatings, biopsy of patches, scrapings of nasal mucosa, and urine are accepted.
Is fasting required before the test?
No, fasting is not required for this test.
How long does it take to get the results?
Reports are available on the 3rd working day after sample collection.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across major cities in India.
What is the sensitivity of this test?
The test can detect as few as 10 copies of M. leprae RNA, making it highly sensitive.
Can this test differentiate between active and past infection?
Since it detects RNA, which is less stable than DNA, a positive result is more likely to indicate active infection.
Is this test covered by insurance?
Coverage depends on your insurance provider. We recommend checking with them directly.
What should I do if my result is positive?
Consult a physician immediately for appropriate treatment. Early treatment can prevent complications and reduce transmission.
Are there any risks associated with sample collection?
Risks are minimal, including slight discomfort or bleeding at the collection site.
Can this test be done for children?
Yes, the test is suitable for all age groups, including children.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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