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MYBPC3 Gene Cardiomyopathy, familial hypertrophic type 4 NGS Genetic Test

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MYBPC3 Gene Cardiomyopathy, familial hypertrophic type 4 NGS Genetic Test

Short Name: MYBPC3 Gene Cardiomyopathy NGS Test

Also known as: MYBPC3 Gene Test, Hypertrophic Cardiomyopathy Genetic Test, FHC Type 4 Genetic Test

MYBPC3 Gene Cardiomyopathy, familial hypertrophic type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify pathogenic mutations in the MYBPC3 gene that cause familial hypertrophic cardiomyopathy type 4, enabling early diagnosis, family screening, and personalized management strategies.

Test Code
5231
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Genetic counseling session recommended to discuss test implications and draw a family pedigree chart.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or use of FTA card for one drop of blood.

Step 3

Report Delivery

Sample sent to laboratory for NGS analysis; results available in 3-4 weeks.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Undergo genetic counseling to understand benefits, risks, and implications of testing.
2
During the Test:Simple blood draw or finger-prick for sample collection.
3
After the Test:Wait for results and schedule follow-up with a genetic counselor or cardiologist for interpretation.

About This Test

Who Should Get This Test

To identify pathogenic mutations in the MYBPC3 gene that cause familial hypertrophic cardiomyopathy type 4, enabling early diagnosis, family screening, and personalized management strategies.

How to Prepare

  • Ensure proper identification and consent
  • Use sterile collection tubes
  • Label samples correctly
  • Transport at room temperature if using blood tubes

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for MYBPC3 mutations is crucial for early diagnosis, risk stratification, and management of familial hypertrophic cardiomyopathy, helping to prevent sudden cardiac events."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect labeling or missing consent

Understanding Your Results

Results indicate the presence or absence of mutations in the MYBPC3 gene. Positive results suggest a genetic cause for hypertrophic cardiomyopathy, while negative results may not rule out other genetic or non-genetic causes.
📊

Pathogenic variant detected

Confirms genetic diagnosis of familial hypertrophic cardiomyopathy type 4; risk assessment and family screening recommended.

📊

Likely pathogenic variant detected

Probable genetic cause; further clinical correlation and counseling advised.

📊

Variant of uncertain significance (VUS)

Mutation identified but clinical significance unknown; repeat testing or family studies may be needed.

📊

No pathogenic variant detected

MYBPC3 mutations not found; consider other genetic tests or clinical evaluation.

⚠️ When to Consult a Doctor:

If you experience symptoms like chest pain or shortness of breath, have a family history of heart disease, or receive abnormal genetic test results, consult a cardiologist or genetic counselor promptly.

Limitations

  • ⚠May not detect all types of mutations (e.g., large deletions/duplications)
  • ⚠Results require interpretation by a genetic specialist
  • ⚠Does not replace clinical evaluation or other diagnostic tests

Risks & Considerations

  • ●Minimal risk from blood draw (e.g., bruising, infection)
  • ●Psychological impact of genetic results (e.g., anxiety, family dynamics)

Interfering Factors

  • ●Sample contamination or degradation
  • ●Insufficient DNA quality or quantity
  • ●Technical errors in sequencing or analysis

Frequently Asked Questions

What is the MYBPC3 Gene Cardiomyopathy NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the MYBPC3 gene, which is associated with familial hypertrophic cardiomyopathy type 4.
Who should consider this test?
Individuals with a family history of hypertrophic cardiomyopathy, symptoms like chest pain or shortness of breath, or abnormal cardiac test results.
What is the cost of the test in India?
The cost is INR 20000.0, which includes sample collection, analysis, and a genetic counseling session.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India in numerous cities.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What sample is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Do I need to fast before the test?
No, fasting is not required for this genetic test.
What do the results mean?
Results indicate if pathogenic mutations are present in the MYBPC3 gene. A positive result confirms genetic predisposition, while negative results may require further testing.
Is genetic counseling necessary?
Yes, genetic counseling is recommended before and after testing to understand implications and guide decision-making.
Can this test diagnose other types of cardiomyopathy?
This test specifically targets MYBPC3 gene mutations for familial hypertrophic cardiomyopathy type 4. Other genetic panels may be needed for different types.
What should I do if I receive a positive result?
Consult a cardiologist or genetic counselor for risk assessment, family screening, and management plans.
Is the test covered by insurance?
Coverage varies by insurance plan; it is advisable to check with your provider. DNA Labs India offers transparent pricing and reports.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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