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MYLK2 Gene Cardiomyopathy, hypertrophic, midventricular, digenic NGS Genetic Test

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MYLK2 Gene Cardiomyopathy, hypertrophic, midventricular, digenic NGS Genetic Test

Short Name: MYLK2 Cardiomyopathy NGS Test

Also known as: MYLK2 Gene Test, Hypertrophic Cardiomyopathy Genetic Test, Digenic NGS Cardiomyopathy Test

MYLK2 Gene Cardiomyopathy, hypertrophic, midventricular, digenic NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the MYLK2 gene and associated genes using next-generation sequencing for the diagnosis and risk assessment of hypertrophic midventricular cardiomyopathy.

Test Code
5255
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Provide detailed clinical history and family pedigree information.

Method: Venipuncture or Blood drop

Step 2

Laboratory Analysis

A trained phlebotomist will collect a blood sample via venipuncture or a blood drop on an FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Resume normal activities immediately.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:No special preparation required. Provide clinical history and genetic counseling if needed.
2
During the Test:Blood sample collection is quick and minimally invasive.
3
After the Test:Resume normal activities. Results will be available in 3-4 weeks.

About This Test

Who Should Get This Test

To identify mutations in the MYLK2 gene and associated genes using next-generation sequencing for the diagnosis and risk assessment of hypertrophic midventricular cardiomyopathy.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection equipment
  • Label samples accurately
  • Transport samples at recommended temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for MYLK2 mutations is essential for accurate diagnosis and personalized management of hypertrophic cardiomyopathy, helping to prevent complications and guide family screening."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5-10 ml blood
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture or Blood drop

Sample Stability

Blood sample stable for 48 hours at 2-8°C
FTA card stable at room temperature for extended periods
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Improper labeling or storage

Understanding Your Results

Results indicate the presence or absence of mutations in the MYLK2 gene and related genes. Positive results suggest an increased risk for hypertrophic cardiomyopathy, while negative results may not rule out other genetic causes.
📊

Positive for MYLK2 mutation

Increased risk of hypertrophic cardiomyopathy; genetic counseling and cardiac monitoring recommended.

📊

Negative for mutations

No pathogenic variants detected in tested genes; clinical correlation and further testing may be needed.

📊

Variant of uncertain significance

Further research and family studies required to determine clinical significance.

⚠️ When to Consult a Doctor:

If you experience symptoms like chest pain, shortness of breath, or have a family history of cardiomyopathy, consult a cardiologist or geneticist for evaluation.

Limitations

  • ⚠Cannot detect all genetic variants
  • ⚠May require confirmatory testing
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Genetic testing may have psychological implications; counseling is recommended

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Hemolyzed blood sample

Compare With Similar Tests

TestMYLK2 Gene Cardiomyopathy, hypertrophic, midventricular, digenic NGS Genetic Test
ComparisonMYLK2 Gene Cardiomyopathy, hypertrophic, midventricular, digenic NGS Genetic TestProvides detailed imaging of heart structure but does not identify genetic mutations.Assesses heart function and hypertrophy but lacks genetic specificity.Tests one gene at a time, while NGS covers multiple genes simultaneously.

Frequently Asked Questions

What is MYLK2 Gene Cardiomyopathy?
It is a rare genetic disorder causing hypertrophic cardiomyopathy in the midventricular heart region due to MYLK2 gene mutations.
What are the common symptoms?
Symptoms include chest pain, shortness of breath, fatigue, dizziness, and fainting, which may worsen over time.
How is this condition diagnosed?
Diagnosis involves echocardiograms, ECGs, cardiac MRI, and genetic testing to identify MYLK2 mutations.
What is the digenic NGS Genetic Test?
It is a comprehensive next-generation sequencing test that analyzes multiple genes, including MYLK2, for mutations linked to cardiomyopathy.
What is the cost of the test?
The test costs INR 20000 at DNA Labs India, with home sample collection available.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates a mutation in the MYLK2 gene, increasing the risk of hypertrophic cardiomyopathy, requiring further monitoring.
What if the test is negative?
A negative result means no pathogenic variants were detected, but clinical correlation and additional testing may be necessary.
Is genetic counseling provided?
Yes, genetic counseling is included to help interpret results and discuss implications for family members.
Can this test be done for children?
Yes, the test can be performed on individuals of all ages, but parental consent is required for minors.
How accurate is the test?
The test uses advanced NGS technology with high accuracy, but results should be interpreted by a genetic specialist.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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