Newborn Screening Panel: NBS Quad Test
Also known as: NBS QUAD Test, Newborn Screening QUAD Panel
Newborn Screening Panel: NBS Quad Test test available at DNA Labs India for ₹1,170. Uses Fluoroimmunoassay on Heel prick blood on filter paper samples. Results in Reports available the next day after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The NBS Quad Test is designed to screen newborns for four critical conditions: Phenylketonuria (PKU), Cystic Fibrosis, Hypothyroidism, and Biotinidase Deficiency, enabling early intervention and treatment.
- Test Code
- 1303
- Price
- ₹1,170
- Sample Type
- Heel prick blood on filter paper
- Result Time
- Reports available the next day after sample receipt.
- Fasting Required
- No
- Method
- Fluoroimmunoassay
Sample Collection
Ensure clinical details and drug history are provided. No special preparation needed for the baby.
Method: Heel prick
Laboratory Analysis
A trained phlebotomist will perform a heel prick to collect blood drops on filter paper.
Report Delivery
Apply a small bandage to the heel. Monitor for any signs of discomfort or infection.
Timeline: Reports available the next day after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The NBS Quad Test is designed to screen newborns for four critical conditions: Phenylketonuria (PKU), Cystic Fibrosis, Hypothyroidism, and Biotinidase Deficiency, enabling early intervention and treatment.
How to Prepare
- Provide clinical details and drug history with the sample
- Collect sample as per protocol
- Ship refrigerated or frozen if necessary
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early newborn screening is vital for the timely diagnosis and management of metabolic disorders, ensuring better health outcomes for infants."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Contaminated or hemolyzed sample
- Missing clinical information
Understanding Your Results
Elevated phenylalanine levels may indicate PKU.
Abnormal immunoreactive trypsinogen (IRT) levels may suggest CF.
Elevated TSH levels may indicate hypothyroidism.
Low biotinidase activity may indicate BTD.
If the test results are abnormal or if the baby shows any symptoms of the screened conditions, consult a pediatrician or geneticist immediately.
Limitations
- ⚠Screening test, not confirmatory
- ⚠False positives possible
- ⚠May require follow-up testing
Risks & Considerations
- ●Minor pain or discomfort from heel prick
- ●Small risk of bruising or infection
- ●Emotional stress for parents
Interfering Factors
- ●Medications affecting hormone levels
- ●Premature birth
- ●Sample handling errors
Frequently Asked Questions
What is the NBS Quad Test?
Why is the NBS Quad Test important?
What conditions does the NBS Quad Test screen for?
How is the NBS Quad Test performed?
What is the cost of the NBS Quad Test?
When should the NBS Quad Test be done?
What if my baby's test result is positive?
Are there any risks associated with the NBS Quad Test?
How accurate is the NBS Quad Test?
Is the test painful for the baby?
How long does it take to get the results?
Can the NBS Quad Test be done at home?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.
