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NOS2 Gene Hypertension, susceptibility to NGS Genetic Test

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NOS2 Gene Hypertension, susceptibility to NGS Genetic Test

Short Name: NOS2 Hypertension NGS Test

Also known as: NOS2 Hypertension Genetic Test, Nitric Oxide Synthase 2 Hypertension Susceptibility Test

NOS2 Gene Hypertension, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To determine an individual's genetic susceptibility to hypertension by analyzing variations in the NOS2 gene using next-generation sequencing, aiding in personalized risk assessment and management.

Test Code
5332
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Provide detailed clinical history and undergo genetic counseling to draw a pedigree chart of affected family members.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or finger prick onto an FTA card, performed by a trained phlebotomist.

Step 3

Report Delivery

Sample is transported to the lab under ambient conditions for DNA extraction and NGS analysis. Results are available in 3-4 weeks.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss family history, test implications, and obtain informed consent.
2
During the Test:Non-invasive blood sample collection; procedure takes approximately 10-15 minutes.
3
After the Test:Report generation and delivery via online portal, email, or WhatsApp; follow-up consultation recommended.

About This Test

Who Should Get This Test

To determine an individual's genetic susceptibility to hypertension by analyzing variations in the NOS2 gene using next-generation sequencing, aiding in personalized risk assessment and management.

How to Prepare

  • Ensure proper identification and prescription
  • Avoid strenuous activity before sample collection
  • Follow any specific instructions from the healthcare provider

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Genetic testing for hypertension susceptibility can guide personalized treatment plans, lifestyle modifications, and early interventions to reduce cardiovascular risks."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture

Sample Stability

Blood in EDTA tube: Stable for 24 hours at room temperature
FTA Card: Stable for several years if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Incorrect sample container or labeling errors

Understanding Your Results

Results indicate genetic susceptibility to hypertension based on identified NOS2 gene variants, guiding further clinical evaluation and management.
Positive result: Pathogenic variants detected, suggesting increased risk; recommend lifestyle modifications and regular monitoring
Negative result: No pathogenic variants detected, indicating lower genetic risk; maintain standard hypertension screening
Variant of uncertain significance: Further testing or family studies may be required for clarification
⚠️ When to Consult a Doctor:

Consult a cardiologist or geneticist if results show increased susceptibility, for personalized management plans including medication, diet, and exercise.

Limitations

  • ⚠Test only analyzes the NOS2 gene, not all hypertension-related genes
  • ⚠Does not diagnose hypertension, only indicates genetic susceptibility
  • ⚠Environmental and lifestyle factors are not assessed
  • ⚠Results may not predict disease onset or severity accurately

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising, pain, or infection at the collection site
  • ●Psychological impact of genetic risk information

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Recent blood transfusion or stem cell transplant
  • ●Sample mishandling or improper storage

Compare With Similar Tests

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ComparisonNOS2 Gene Hypertension, susceptibility to NGS Genetic Test

Frequently Asked Questions

What is the NOS2 Gene Hypertension NGS Genetic Test?
It is a genetic test that uses next-generation sequencing to analyze variations in the NOS2 gene, which is linked to hypertension susceptibility.
Who should consider this test?
Individuals with a family history of hypertension, early onset hypertension, or those seeking personalized risk assessment.
How is the test performed?
A blood sample is collected and analyzed in the lab using NGS technology to identify NOS2 gene variants.
What is the cost of the test?
The test costs INR 20,000, with free home sample collection available across India.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the results indicate?
Results show genetic susceptibility to hypertension based on NOS2 gene variations, not a diagnosis of hypertension.
Is the test accurate?
The test uses advanced NGS technology for high accuracy, but results should be interpreted in conjunction with clinical evaluation.
Are there any risks associated with the test?
Risks are minimal, primarily related to blood draw, such as bruising or infection.
Can this test diagnose hypertension?
No, it only assesses genetic susceptibility; hypertension is diagnosed through blood pressure measurements.
What should I do after receiving the results?
Consult a healthcare professional, such as a cardiologist or geneticist, to discuss management strategies.
Does DNA Labs India provide raw data files?
Yes, DNA Labs India shares Raw Data, FASTQ, and VCF files along with the clinical report for transparency.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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