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NPPA Gene Atrial fibrillation type 6 NGS Genetic Test

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NPPA Gene Atrial fibrillation type 6 NGS Genetic Test

Also known as: NPPA Gene Atrial Fibrillation Type 6 Test

NPPA Gene Atrial fibrillation type 6 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next-Generation Sequencing) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the NPPA gene associated with atrial fibrillation type 6, aiding in early diagnosis, risk assessment, and personalized management of the condition.

Test Code
2501
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS (Next-Generation Sequencing)
Step 1

Sample Collection

Genetic counseling recommended to discuss implications and obtain informed consent.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or use of FTA card for one drop of blood.

Step 3

Report Delivery

Sample is processed and sent to the laboratory for NGS analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to draw a family pedigree chart and discuss test implications.
2
During the Test:Sample collection via blood draw or FTA card, followed by laboratory processing.
3
After the Test:Report generation with detailed findings, and consultation to discuss results and next steps.

About This Test

Who Should Get This Test

To identify mutations in the NPPA gene associated with atrial fibrillation type 6, aiding in early diagnosis, risk assessment, and personalized management of the condition.

How to Prepare

  • Ensure proper sample handling and labeling
  • Use sterile collection equipment
  • Follow instructions for FTA card if applicable
  • Maintain sample stability during transport

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for NPPA mutations can guide personalized treatment and risk assessment for atrial fibrillation type 6, especially in individuals with a family history."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture

Sample Stability

Blood: Up to 24 hours at room temperature
Extracted DNA: Stable for several days if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improper labeling or documentation

Understanding Your Results

This test detects pathogenic mutations in the NPPA gene linked to atrial fibrillation type 6. Results should be interpreted by a healthcare professional in the context of clinical history and family background.
Positive Result: Pathogenic variant detected, indicating increased risk for atrial fibrillation type 6; further clinical evaluation and monitoring recommended.
Negative Result: No pathogenic variants detected; does not rule out atrial fibrillation from other causes.
Variant of Uncertain Significance (VUS): Genetic change identified but clinical significance unclear; may require additional testing or family studies.
⚠️ When to Consult a Doctor:

If you have a family history of atrial fibrillation, experience symptoms like palpitations, shortness of breath, fatigue, dizziness, or chest pain, or if you receive a positive or uncertain test result.

Limitations

  • ⚠May not detect all genetic variants or mutations
  • ⚠Results require clinical correlation and genetic counseling
  • ⚠Not diagnostic for all cases of atrial fibrillation; other factors may contribute

Risks & Considerations

  • ●Minimal risk from blood draw (e.g., bruising, infection)
  • ●Potential psychological impact of genetic results
  • ●No significant physical risks associated with the test itself

Interfering Factors

  • ●Sample degradation or contamination
  • ●Technical errors during sequencing
  • ●Insufficient DNA quality or quantity

Frequently Asked Questions

What is the NPPA Gene Atrial Fibrillation Type 6 NGS Genetic Test?
This test uses next-generation sequencing to detect mutations in the NPPA gene associated with atrial fibrillation type 6, a heart rhythm disorder with early onset and higher complication risk.
Why is this test important?
It helps identify genetic risk factors for atrial fibrillation type 6, enabling early diagnosis, personalized treatment, and proactive management to reduce complications like stroke or heart failure.
Who should consider getting this test?
Individuals with a family history of atrial fibrillation, those experiencing symptoms such as palpitations or shortness of breath, or those referred for genetic counseling due to cardiac concerns.
How is the test performed?
A blood sample or one drop of blood on an FTA card is collected and analyzed using NGS technology to sequence the NPPA gene for mutations.
What is the cost of the test?
The test costs INR 20000.0, which includes home sample collection, genetic counseling, and a comprehensive clinical report.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the results mean?
A positive result indicates a pathogenic mutation in the NPPA gene, increasing risk for atrial fibrillation type 6. Negative means no such mutations detected. Variants of uncertain significance may require further evaluation.
Is the test covered by insurance?
Coverage varies by insurance provider and policy. It is not typically covered under government schemes like PMJAY or CGHS; check with your insurer for details.
Are there any risks associated with the test?
Risks are minimal, primarily related to blood draw (e.g., bruising). There may be psychological impacts from genetic results, so genetic counseling is recommended.
How can I prepare for the test?
No fasting is required. Attend a genetic counseling session to discuss family history and provide informed consent. Ensure proper documentation for sample collection.
What if the test is positive?
A positive result requires consultation with a healthcare provider for further evaluation, monitoring, and potential treatment options to manage atrial fibrillation risk.
Can this test diagnose atrial fibrillation?
No, this test identifies genetic mutations that increase risk for atrial fibrillation type 6. Diagnosis of atrial fibrillation itself requires clinical tests like ECG or echocardiogram.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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