Skip to main content
DNA Labs India

PLS3 Gene Bone mineral density QTL18, osteoporosis NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

PLS3 Gene Bone mineral density QTL18, osteoporosis NGS Genetic Test

Short Name: PLS3 Osteoporosis NGS Test

Also known as: PLS3 Gene Test for Osteoporosis, Bone Mineral Density QTL18 Genetic Test

PLS3 Gene Bone mineral density QTL18, osteoporosis NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the PLS3 Gene Osteoporosis NGS Genetic Test is to identify genetic variants in the PLS3 gene that are associated with reduced bone mineral density and increased risk of osteoporosis. This test aids in the early diagnosis and risk assessment for osteoporosis, enabling personalized preventive measures and treatment plans.

Test Code
4859
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and genetic counseling.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample will be collected via venipuncture by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Consult with a healthcare provider for genetic counseling. Provide family medical history.
2
During the Test:The test involves a blood draw. The sample is sent to the lab for NGS analysis.
3
After the Test:Wait for results, which take 3-4 weeks. Discuss results with a genetic counselor or doctor.

About This Test

Who Should Get This Test

The purpose of the PLS3 Gene Osteoporosis NGS Genetic Test is to identify genetic variants in the PLS3 gene that are associated with reduced bone mineral density and increased risk of osteoporosis. This test aids in the early diagnosis and risk assessment for osteoporosis, enabling personalized preventive measures and treatment plans.

How to Prepare

  • Bring identification and doctor's prescription
  • Inform about any medications or supplements
  • Ensure proper labeling of the sample

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for PLS3 gene mutations can provide valuable insights into osteoporosis risk, aiding in early intervention and personalized management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood samples are stable for 48 hours at room temperature
Extracted DNA can be stored at -20°C for long-term
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated sample
  • Improper labeling

Understanding Your Results

Interpretation of the PLS3 Gene Osteoporosis NGS Genetic Test results should be done by a qualified geneticist or healthcare provider. The presence of pathogenic variants in the PLS3 gene indicates an increased risk for osteoporosis.
📊

No pathogenic variants detected

Low genetic risk for osteoporosis related to PLS3 gene. Continue standard bone health practices.

📊

Pathogenic variants detected

Increased genetic risk for osteoporosis. Recommend bone density testing, lifestyle modifications, and possible medical intervention.

⚠️ When to Consult a Doctor:

If pathogenic variants are detected, or if you have symptoms of osteoporosis such as back pain, loss of height, or fractures, consult an endocrinologist or orthopedic specialist.

Limitations

  • ⚠Test is limited to PLS3 gene mutations only
  • ⚠Does not cover all genetic causes of osteoporosis
  • ⚠Results should be correlated with clinical findings and other diagnostic tests

Risks & Considerations

  • ●Minimal risk from blood draw: bruising, infection
  • ●Psychological impact of genetic results

Compare With Similar Tests

TestPLS3 Gene Bone mineral density QTL18, osteoporosis NGS Genetic TestDEXA ScanBlood Calcium Test
ComparisonPLS3 Gene Bone mineral density QTL18, osteoporosis NGS Genetic Test

Frequently Asked Questions

What is the PLS3 Gene Osteoporosis NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the PLS3 gene, which is associated with bone mineral density and osteoporosis risk.
Who should consider getting this test?
Individuals with a family history of osteoporosis, postmenopausal women, those with low bone density, or anyone with risk factors for osteoporosis should consider this test.
How is the test performed?
A blood sample is collected and analyzed using NGS technology to identify variants in the PLS3 gene.
What is the cost of the PLS3 Gene Osteoporosis NGS Genetic Test?
The test costs INR 20000 at DNA Labs India, with home sample collection available.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What do the results of this test mean?
Results indicate whether pathogenic variants in the PLS3 gene are detected, which can inform osteoporosis risk and guide further management.
Can this test diagnose osteoporosis?
This test identifies genetic risk for osteoporosis but does not diagnose the condition itself. Diagnosis requires clinical evaluation and bone density testing.
What are the risks associated with this test?
Risks are minimal, primarily related to blood draw, such as bruising or infection. There may be psychological impacts from genetic results.
How accurate is the PLS3 Gene Osteoporosis NGS Genetic Test?
NGS technology is highly accurate for detecting genetic variants, but results should be interpreted in the context of clinical findings.
Do I need a doctor's prescription for this test?
It is recommended to have a doctor's prescription and genetic counseling before undergoing the test.
What should I do if the test shows pathogenic variants?
Consult a healthcare provider for further evaluation, such as bone density testing, and discuss preventive measures or treatments.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

WISP3 Gene Arthropathy, progressive pseudorheumatoid, of childhood NGS Genetic Test

₹20,000

FLNB Gene Atelosteogenesis type 3 NGS Genetic Test

₹20,000

FLNB Gene Atelosteogenesis type 1 NGS Genetic Test

₹20,000

EBP Gene Chondrodysplasia punctata, X-linked dominant NGS Genetic Test

₹20,000

COL11A1 Gene Marshall syndrome NGS Genetic Test

₹20,000

ACTN3 (Sports Gene) Genotyping Test

₹7,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.