Pneumosystis Carinii (RNA Detection) Qualitative Test
Short Name: PCP RNA Qualitative
Also known as: Pneumocystis jirovecii RNA Detection, PCP PCR Qualitative, Pneumocystis carinii PCR
Pneumosystis Carinii (RNA Detection) Qualitative Test test available at DNA Labs India for ₹8,500. Uses Real-Time RT-PCR on Fresh tissue biopsy specimens, skin biopsy, tissue specimens from various body sites, peripheral blood, respiratory secretions samples. Results in Reports are available on the 4th working day. Email delivery within 48 hours, phone within 36 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The primary purpose of the Pneumocystis Carinii (RNA Detection) Qualitative Test is to diagnose Pneumocystis jirovecii infection, especially in immunocompromised patients presenting with respiratory symptoms. It is used to confirm PCP in individuals with suspected infection, monitor treatment response, and differentiate PCP from other pulmonary infections. The test's high sensitivity allows detection even when organism load is low, which is critical in early-stage infection or in patients with atypical presentations.
- Test Code
- 6235
- CPT Code
- 87798
- ICD Code
- B59
- Price
- ₹8,500
- Sample Type
- Fresh tissue biopsy specimens, skin biopsy, tissue specimens from various body sites, peripheral blood, respiratory secretions
- Result Time
- Reports are available on the 4th working day. Email delivery within 48 hours, phone within 36 hours.
- Fasting Required
- No
- Method
- Real-Time RT-PCR
Sample Collection
No special preparation is required. However, patients must sign a consent document and provide relevant clinical history. Inform your healthcare provider about any medications you are taking, especially antibiotics or antifungals.
Method: Biopsy, blood draw, or respiratory secretion collection
Laboratory Analysis
The sample collection procedure depends on the specimen type. For respiratory secretions, a sputum sample or bronchoalveolar lavage may be collected. For tissue biopsy, a minor surgical procedure is performed. Blood samples are drawn from a vein. All procedures are performed by trained professionals.
Report Delivery
After sample collection, you can resume normal activities. If a biopsy was performed, follow your doctor's instructions for wound care. Results are typically available within 4 working days.
Timeline: Reports are available on the 4th working day. Email delivery within 48 hours, phone within 36 hours.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Pneumocystis Carinii (RNA Detection) Qualitative Test is to diagnose Pneumocystis jirovecii infection, especially in immunocompromised patients presenting with respiratory symptoms. It is used to confirm PCP in individuals with suspected infection, monitor treatment response, and differentiate PCP from other pulmonary infections. The test's high sensitivity allows detection even when organism load is low, which is critical in early-stage infection or in patients with atypical presentations.
How to Prepare
- Ensure sterile collection containers are used
- Label the sample with patient identification details
- Transport samples to the laboratory immediately or store as per instructions
- For tissue specimens, place in appropriate transport medium
- Maintain cold chain if required
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"Early detection of Pneumocystis jirovecii is critical in immunocompromised patients. This qualitative RNA test offers high sensitivity, enabling timely intervention and improved outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Improper labeling
- Sample in inappropriate container
- Hemolyzed blood samples
- Samples not transported within recommended time
Understanding Your Results
Positive
Pneumocystis jirovecii RNA detected. Consistent with active PCP infection. Clinical correlation and treatment initiation are recommended.
Negative
Pneumocystis jirovecii RNA not detected. PCP is less likely, but if clinical suspicion remains high, consider repeat testing or alternative diagnostics.
Consult your healthcare provider if you have symptoms such as persistent cough, fever, shortness of breath, or chest pain, especially if you are immunocompromised. Early diagnosis and treatment are crucial for better outcomes.
Limitations
- ⚠Qualitative test does not quantify organism load
- ⚠Negative result does not completely rule out PCP; clinical correlation required
- ⚠Requires specialized laboratory equipment and trained personnel
- ⚠May not detect very low levels of the organism in early infection
Risks & Considerations
- ●Minimal risk of bleeding or infection at biopsy site
- ●Discomfort during blood draw
- ●Rare complications from bronchoscopy if performed
Interfering Factors
- ●Improper sample collection or handling may lead to false negatives
- ●Inhibitors in the sample (e.g., blood, mucus) can affect RT-PCR
- ●Prior antibiotic or antifungal therapy may reduce organism load
- ●Contamination during collection can cause false positives
Compare With Similar Tests
| Test | Pneumosystis Carinii (RNA Detection) Qualitative Test | Chest X-ray | Bronchoscopy with BAL | Antibody detection | Conventional PCR |
|---|---|---|---|---|---|
| Comparison | Pneumosystis Carinii (RNA Detection) Qualitative Test | Imaging may show bilateral interstitial infiltrates but is not specific for PCP. RNA test provides definitive diagnosis. | BAL fluid can be used for RNA test, increasing sensitivity. RNA test is more sensitive than microscopy. | Antibody tests are less reliable in immunocompromised patients. RNA test detects the organism directly. | RT-PCR for RNA is more sensitive than DNA PCR as it detects active transcription. |
Frequently Asked Questions
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₹4,500Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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