SCN4B Gene Long QT syndrome type 10 NGS Genetic Test
Short Name: SCN4B LQTS Type 10 NGS Test
Also known as: LQTS Type 10, SCN4B-related Long QT Syndrome, Long QT Syndrome 10
SCN4B Gene Long QT syndrome type 10 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the SCN4B gene associated with Long QT Syndrome Type 10 for accurate diagnosis, risk assessment, and personalized management of cardiac arrhythmias.
- Test Code
- 5267
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with Long QT Syndrome. No fasting required.
Method: Blood draw
Laboratory Analysis
A blood sample is drawn from a vein in the arm. For FTA card collection, a single drop of blood is applied.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the SCN4B gene associated with Long QT Syndrome Type 10 for accurate diagnosis, risk assessment, and personalized management of cardiac arrhythmias.
How to Prepare
- Ensure patient identification and consent
- Use sterile equipment for blood draw
- Label samples correctly with patient details
- Store samples at appropriate temperature until transport
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for Long QT Syndrome Type 10 is crucial for early diagnosis and management, especially in families with a history of sudden cardiac events. This NGS test provides accurate detection of SCN4B mutations."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrectly labeled or unlabeled samples
Understanding Your Results
No pathogenic variants detected
Negative for SCN4B-related Long QT Syndrome Type 10. Clinical correlation recommended if symptoms persist.
Pathogenic variant detected
Positive for SCN4B-related Long QT Syndrome Type 10. Genetic counseling and cardiac evaluation advised for management.
Variant of Uncertain Significance (VUS)
Further testing and family studies may be needed to determine clinical significance.
Likely pathogenic variant
High probability of association with LQTS10. Consult a genetic specialist for guidance.
Consult a doctor if you experience symptoms like fainting, rapid heartbeat, or chest pain, especially with a family history of Long QT Syndrome or sudden cardiac death. After receiving test results, seek genetic counseling for interpretation and management.
Limitations
- ⚠This test does not detect all genetic causes of Long QT Syndrome
- ⚠Results may include variants of uncertain significance (VUS) requiring further evaluation
- ⚠Does not assess for other cardiac conditions or environmental factors
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection at the puncture site
- ●Psychological impact of genetic results, requiring counseling support
Interfering Factors
- ●Contaminated or degraded DNA samples
- ●Recent blood transfusions may affect results
- ●Technical errors in sample collection or processing
Compare With Similar Tests
| Test | SCN4B Gene Long QT syndrome type 10 NGS Genetic Test | KCNQ1 Gene Long QT Syndrome Type 1 NGS Test | KCNH2 Gene Long QT Syndrome Type 2 NGS Test | SCN5A Gene Long QT Syndrome Type 3 NGS Test | Comprehensive Cardiac Arrhythmia Panel |
|---|---|---|---|---|---|
| Comparison | SCN4B Gene Long QT syndrome type 10 NGS Genetic Test |
Frequently Asked Questions
What is SCN4B Gene Long QT Syndrome Type 10?
How is the SCN4B Gene Long QT Syndrome Type 10 NGS Genetic Test performed?
What are the symptoms of Long QT Syndrome Type 10?
Who should consider this genetic test?
What is the cost of the test at DNA Labs India?
How long does it take to get results?
Is fasting required before the test?
What sample types are accepted?
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