Skip to main content
DNA Labs India

SCNN1A Gene Bronchiectasis with or without elevated sweat chloride type 2 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

SCNN1A Gene Bronchiectasis with or without elevated sweat chloride type 2 NGS Genetic Test

Short Name: SCNN1A Bronchiectasis NGS Test

SCNN1A Gene Bronchiectasis with or without elevated sweat chloride type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

Next Generation Sequencing Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify pathogenic variants in the SCNN1A gene associated with bronchiectasis and elevated sweat chloride, aiding in diagnosis, treatment planning, and genetic counseling.

Test Code
1896
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to assess family history and draw a pedigree chart.

Step 2

Laboratory Analysis

Standard blood draw procedure; alternatively, use extracted DNA or one drop of blood on FTA card.

Step 3

Report Delivery

Sample is processed for DNA extraction and analyzed using NGS technology.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history assessment recommended.
2
During the Test:Blood sample collection; test involves NGS analysis.
3
After the Test:Report generation and interpretation; follow-up with healthcare provider.

About This Test

Who Should Get This Test

To identify pathogenic variants in the SCNN1A gene associated with bronchiectasis and elevated sweat chloride, aiding in diagnosis, treatment planning, and genetic counseling.

How to Prepare

  • No fasting required.
  • Ensure accurate clinical history is provided.
  • Ambient room temperature for sample storage.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for SCNN1A can aid in early diagnosis and personalized management of bronchiectasis, especially in cases with elevated sweat chloride."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Sample Stability

Blood samples stable at room temperature for 48 hours.
FTA card samples stable at room temperature for extended periods.
Sample Rejection Criteria:
  • Hemolyzed or insufficient sample volume.
  • Incorrect labeling or missing patient information.

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the SCNN1A gene, which can inform diagnosis and management of bronchiectasis.
Positive result: Pathogenic variant detected, consistent with SCNN1A-related bronchiectasis.
Negative result: No pathogenic variants detected, but clinical correlation is needed.
Variant of uncertain significance (VUS): Further testing or family studies recommended.
⚠️ When to Consult a Doctor:

Consult a doctor if experiencing respiratory symptoms, have a family history of bronchiectasis, or after receiving genetic test results for personalized management.

Limitations

  • ⚠Test may not detect all genetic variants related to bronchiectasis.
  • ⚠Results require interpretation by a genetic counselor or healthcare provider.
  • ⚠Does not replace clinical evaluation.

Risks & Considerations

  • ●Minimal risks from blood draw, such as bruising, bleeding, or infection at the site.

Frequently Asked Questions

What is SCNN1A gene bronchiectasis?
It is a type of bronchiectasis caused by mutations in the SCNN1A gene, which regulates salt and water in the lungs, often associated with elevated sweat chloride levels.
What are the symptoms of SCNN1A gene bronchiectasis?
Symptoms include chronic coughing, shortness of breath, wheezing, chest pain, and frequent lung infections.
How is SCNN1A gene bronchiectasis diagnosed?
Diagnosis involves medical history, physical exam, and tests like chest X-ray, CT scan, sputum culture, pulmonary function test, sweat chloride test, and genetic testing for SCNN1A mutations.
What is the cost of the SCNN1A genetic test in India?
The cost is approximately INR 20,000 for the NGS genetic test at DNA Labs India.
Is genetic testing necessary for bronchiectasis?
Genetic testing can identify specific causes like SCNN1A mutations, guiding treatment and assessing family risk, especially when other causes are ruled out.
How is the genetic test performed?
The test uses next-generation sequencing (NGS) on a blood sample, extracted DNA, or one drop of blood on an FTA card.
What do the test results mean?
Results show whether pathogenic variants in the SCNN1A gene are detected, which can confirm diagnosis and inform management strategies.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
How long does it take to get the test results?
Reports are typically available in 3 to 4 weeks.
Can this test be done for children?
Yes, the test is applicable to all ages, but genetic counseling is recommended for pediatric cases.
What treatment options are based on test results?
Positive results may guide targeted therapies, antibiotics for infections, airway clearance techniques, and genetic counseling for family planning.
How should variants of uncertain significance be interpreted?
Variants of uncertain significance require further clinical correlation, family studies, or additional testing; consult a genetic counselor for guidance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Alpha-1-Antitrypsin (AAT) Phenotype Test

₹18,000

Pulmonary panel NGS Genetic Test

₹20,000

DNAI1 Gene Primary ciliary dyskinesia type 1 NGS Genetic Test

₹20,000

RSPH9 Gene Primary ciliary dyskinesia type 12 NGS Genetic Test

₹20,000

DNAL1 Gene Primary ciliary dyskinesia type 16 NGS Genetic Test

₹20,000

DNAAF3 Gene Primary ciliary dyskinesia type 2 NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.