SLC10A2 Gene Bile acid malabsorption, primary NGS Genetic Test
Short Name: SLC10A2 BAM Genetic Test
Also known as: Primary Bile Acid Malabsorption Test, SLC10A2 Mutation Analysis, BAM Genetic Test
SLC10A2 Gene Bile acid malabsorption, primary NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 2-3 weeks from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose primary bile acid malabsorption by identifying pathogenic mutations in the SLC10A2 gene using NGS technology, aiding in clinical decision-making and family planning.
- Test Code
- 4643
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 2-3 weeks from sample receipt
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide detailed clinical history and undergo genetic counseling to draw a pedigree chart of family members affected with bile acid malabsorption.
Method: Blood draw or saliva collection
Laboratory Analysis
Sample collection via blood draw from a vein or saliva using a sterile kit, performed by a trained phlebotomist.
Report Delivery
Sample is labeled, stored at ambient temperature, and sent to the lab for NGS analysis; results are reviewed by geneticists.
Timeline: 2-3 weeks from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose primary bile acid malabsorption by identifying pathogenic mutations in the SLC10A2 gene using NGS technology, aiding in clinical decision-making and family planning.
How to Prepare
- Ensure patient provides complete clinical history
- Use DNA Labs India collection kit for blood or saliva
- Avoid eating or drinking for 30 minutes before saliva collection
- Label sample correctly with patient details
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for SLC10A2 mutations is essential for diagnosing primary bile acid malabsorption, particularly in patients with chronic gastrointestinal symptoms and family history."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample hemolysis or clotting
- Insufficient sample volume
- Incorrect labeling or missing patient information
Understanding Your Results
Positive for pathogenic variant
Confirms genetic basis for PBAM; recommend clinical correlation and family screening.
Negative for pathogenic variants
No SLC10A2 mutations detected; consider other diagnostic tests for BAM.
Variant of uncertain significance (VUS)
Further testing or family studies may be needed for clarification.
Consult a gastroenterologist or geneticist if symptoms persist, if test results are positive, or for family planning advice regarding PBAM.
Limitations
- ⚠May not detect all possible SLC10A2 mutations
- ⚠Results require interpretation by a genetic counselor
- ⚠Does not rule out other causes of BAM
Risks & Considerations
- ●Minor bruising or pain at blood draw site
- ●Very low risk of infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Poor sample quality or contamination
- ●Hemolyzed blood sample
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | SLC10A2 Gene Bile acid malabsorption, primary NGS Genetic Test | SeHCAT Test | Fecal Fat Test | Endoscopy |
|---|---|---|---|---|
| Comparison | SLC10A2 Gene Bile acid malabsorption, primary NGS Genetic Test |
Frequently Asked Questions
What is the SLC10A2 gene test?
What is primary bile acid malabsorption (PBAM)?
What are the symptoms of PBAM?
How is the test performed?
What sample is required for the test?
How long does it take to get results?
What is the cost of the SLC10A2 gene test?
Is home sample collection available?
What do the test results mean?
Is genetic counseling necessary before the test?
Are there any risks associated with the test?
How accurate is the SLC10A2 gene test?
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