SLC40A1 Gene Hemochromatosis type 4 NGS Genetic Test
Short Name: Hemochromatosis Type 4 Genetic Test
Also known as: Hereditary hemochromatosis type 4, SLC40A1-related iron overload
SLC40A1 Gene Hemochromatosis type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose hemochromatosis type 4 by identifying pathogenic mutations in the SLC40A1 gene using Next-Generation Sequencing, facilitating early management and genetic counseling.
- Test Code
- 4698
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Provide detailed clinical history and undergo a genetic counseling session to draw a pedigree chart of family members affected with hemochromatosis type 4.
Method: Venipuncture
Laboratory Analysis
A blood sample will be collected via venipuncture from a vein in the arm.
Report Delivery
Apply pressure to the puncture site with a cotton ball to prevent bruising and avoid strenuous activity for a few hours.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose hemochromatosis type 4 by identifying pathogenic mutations in the SLC40A1 gene using Next-Generation Sequencing, facilitating early management and genetic counseling.
How to Prepare
- Bring a valid ID and doctor's prescription
- Inform the phlebotomist about any medications or health conditions
- No specific fasting required unless advised by a physician
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Early genetic diagnosis of hemochromatosis type 4 through SLC40A1 gene testing can guide personalized treatment and prevent iron overload complications."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Improper labeling or documentation
Understanding Your Results
Negative
No pathogenic variants detected in the SLC40A1 gene, indicating low risk for hemochromatosis type 4.
Positive
Pathogenic variants detected, confirming diagnosis of hemochromatosis type 4. Further clinical evaluation and treatment are recommended.
Variant of uncertain significance
A genetic variant was found but its clinical significance is unknown. Additional testing or family studies may be needed.
If you experience symptoms of hemochromatosis, have a family history of the condition, or receive abnormal test results, consult a healthcare provider or genetic counselor for further evaluation and management.
Limitations
- ⚠May not detect all possible mutations or variants of uncertain significance
- ⚠Results require interpretation by a genetic counselor or specialist
- ⚠Does not replace clinical evaluation for other causes of iron overload
Risks & Considerations
- ●Minimal physical risk from blood draw, such as bruising or discomfort
- ●Psychological impact of genetic results, including anxiety or stress
- ●Potential for insurance or employment discrimination based on genetic information
Interfering Factors
- ●Poor sample quality or contamination
- ●Technical errors in sequencing or analysis
- ●Insufficient DNA quantity
Frequently Asked Questions
What is hemochromatosis type 4?
What causes hemochromatosis type 4?
What are the symptoms of hemochromatosis type 4?
How is the SLC40A1 gene test performed?
What is the cost of the test?
Is home sample collection available?
How long does it take to get results?
What do the test results mean?
Is the test accurate?
Who should get tested for hemochromatosis type 4?
What is the treatment for hemochromatosis type 4?
Can hemochromatosis type 4 be prevented?
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