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SLCO1B1 Gene Hyperbilirubinemia, Rotor type NGS Genetic Test

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SLCO1B1 Gene Hyperbilirubinemia, Rotor type NGS Genetic Test

Short Name: SLCO1B1 Rotor Type NGS Test

Also known as: Rotor syndrome, SLCO1B1-related hyperbilirubinemia

SLCO1B1 Gene Hyperbilirubinemia, Rotor type NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To diagnose Hyperbilirubinemia, Rotor Type by detecting mutations in the SLCO1B1 gene using NGS technology, aiding in clinical management and genetic counseling.

Test Code
5424
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Genetic counseling session recommended to discuss test implications and draw a family pedigree chart.

Method: Venipuncture or FTA card collection

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site; sample sent to lab for analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history review recommended.
2
During the Test:Blood sample collection via venipuncture or FTA card.
3
After the Test:Results available in 3-4 weeks; follow-up with healthcare provider advised.

About This Test

Who Should Get This Test

To diagnose Hyperbilirubinemia, Rotor Type by detecting mutations in the SLCO1B1 gene using NGS technology, aiding in clinical management and genetic counseling.

How to Prepare

  • Ensure proper identification and consent
  • Use sterile equipment for blood draw
  • Label samples correctly with patient details

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for diagnosing Rotor type hyperbilirubinemia, a rare genetic disorder affecting bilirubin metabolism, and guides appropriate clinical management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA card collection

Sample Stability

Blood samples: stable at room temperature for 24 hours
FTA cards: stable at room temperature for extended periods
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed or contaminated samples
  • Incorrect labeling or missing patient information

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the SLCO1B1 gene. Consult a genetic specialist for detailed interpretation.
📊

Mutation Detected

Confirms diagnosis of Rotor type hyperbilirubinemia; genetic counseling and management recommended.

📊

No Mutation Detected

Reduces likelihood of Rotor type hyperbilirubinemia; consider other causes of symptoms.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like jaundice, dark urine, or have a family history of liver disorders, and after receiving test results for further guidance.

Limitations

  • ⚠May not detect all genetic variants or mutations
  • ⚠Results require interpretation by a genetic specialist
  • ⚠Does not rule out other causes of hyperbilirubinemia

Risks & Considerations

  • ●Minor bruising or discomfort at blood draw site
  • ●Rare risk of infection
  • ●Emotional impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA quality
  • ●Incorrect sample collection or handling

Frequently Asked Questions

What is SLCO1B1 Gene Hyperbilirubinemia, Rotor Type NGS Genetic Test?
It is a genetic test that uses NGS technology to detect mutations in the SLCO1B1 gene, which causes Rotor type hyperbilirubinemia, a rare liver disorder affecting bilirubin metabolism.
How is the test performed?
The test involves collecting a blood sample or extracted DNA, which is then analyzed using Next-Generation Sequencing to identify mutations in the SLCO1B1 gene.
What are the symptoms of Rotor type hyperbilirubinemia?
Symptoms include jaundice (yellowing of skin and eyes), dark urine, pale stools, abdominal pain, nausea, vomiting, and fatigue.
Who should get this test?
Individuals with unexplained jaundice, family history of Rotor syndrome, symptoms of liver disorders, or those undergoing genetic counseling for at-risk family members.
What is the cost of the test?
The cost at DNA Labs India is INR 20000, which includes home sample collection and report delivery.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
What does a positive result mean?
A positive result indicates the presence of a pathogenic mutation in the SLCO1B1 gene, confirming a diagnosis of Rotor type hyperbilirubinemia, and may require further management and genetic counseling.
What are the risks of the test?
Risks are minimal and include minor bruising or discomfort at the blood draw site, rare infection, and potential emotional impact from genetic results.
How accurate is the test?
The test uses advanced NGS technology for high accuracy in detecting mutations, but it may not identify all genetic variants. Interpretation by a genetic specialist is recommended.
Can the test be used for prenatal diagnosis?
This test is typically for diagnostic purposes in symptomatic individuals; prenatal testing may require specialized genetic counseling and different approaches.
What should I do after receiving the results?
Consult a healthcare provider or genetic counselor to understand the results, discuss management options, and consider implications for family members.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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