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DNA Labs India

Soluble Transferrin Receptor (sTfR) Serum Test

DNA Labs India | ISO 9001:2015 Certified

Soluble Transferrin Receptor (sTfR) Serum Test

Short Name: sTfR Serum

Also known as: sTfR, Soluble Transferrin Receptor, sTfR Serum

Soluble Transferrin Receptor (sTfR) Serum Test test available at DNA Labs India for ₹1,755. Uses Nephelometry on Serum samples. Results in Samples are accepted Monday/Thursday by 9 am; reports are issued the same day.. Free home collection in 300+ cities across India.

Blood test🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the sTfR test is to evaluate iron deficiency and provide a supporting marker for differentiating iron deficiency anaemia from anaemia of chronic disease, particularly when ferritin is affected by inflammatory processes.

Test Code
3650
Price
₹1,755
Sample Type
Serum
Result Time
Samples are accepted Monday/Thursday by 9 am; reports are issued the same day.
Fasting Required
No
Method
Nephelometry
Step 1

Sample Collection

No special preparation is required. No fasting is required. Continue regular diet and medications unless advised otherwise.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is collected from a vein in the arm using a sterile needle. The procedure is quick and generally painless.

Step 3

Report Delivery

You may resume normal activities immediately. Apply pressure to the puncture site to prevent bruising.

Timeline: Samples are accepted Monday/Thursday by 9 am; reports are issued the same day.

Patient Instructions

1
Before the Test:No special preparation is needed. No fasting required. Continue your normal routine.
2
During the Test:A blood sample is drawn from a vein. It takes only a few minutes.
3
After the Test:No restrictions. The puncture site may be sore for a short time.

About This Test

Who Should Get This Test

The purpose of the sTfR test is to evaluate iron deficiency and provide a supporting marker for differentiating iron deficiency anaemia from anaemia of chronic disease, particularly when ferritin is affected by inflammatory processes.

How to Prepare

  • No fasting required
  • Inform your doctor about any iron supplements or ongoing medication
  • Sample is collected at any time of the day

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The sTfR assay is especially useful when ferritin is inconclusive due to inflammation. It provides a clearer picture of iron deficiency."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separation Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerator: 1 week
Frozen: 3 months
Sample Rejection Criteria:
  • Hemolyzed sample
  • Incorrectly labelled specimen
  • Sample not stored appropriately
  • Insufficient volume

Understanding Your Results

sTfR is elevated in iron deficiency due to increased transferrin receptors. Normal levels suggest iron stores are adequate.
📊

Suggests iron deficiency; possible IDA.

📊

Iron stores likely adequate; consider anaemia of chronic disease.

📊

May indicate increased erythropoiesis as in haemolysis.

⚠️ When to Consult a Doctor:

Consult a physician if you experience fatigue, weakness, dizziness, shortness of breath, pallor or persistent headaches. A doctor can determine whether sTfR testing is appropriate for your clinical condition.

Limitations

  • Elevated sTfR is not specific to iron deficiency; it may also be high in conditions with expanded erythroid activity.
  • Reference ranges vary with age, gender, assay method and laboratory.
  • Results should be interpreted in conjunction with the complete blood count, serum iron, TIBC, ferritin and clinical findings.

Risks & Considerations

  • Minor bruising
  • Dizziness
  • Rare infection

Interfering Factors

  • Hemolysis or lipemia in the blood sample.
  • Prolonged storage at room temperature.
  • Conditions with increased erythropoiesis such as haemolytic anaemia or thalassaemia can also raise sTfR.

Compare With Similar Tests

TestSoluble Transferrin Receptor (sTfR) Serum Test
ComparisonSoluble Transferrin Receptor (sTfR) Serum Test

Frequently Asked Questions

What is the Soluble Transferrin Receptor (sTfR) Serum Test?
It measures sTfR protein levels in blood, which rise when the body has low iron. It helps diagnose iron deficiency anaemia.
Why is the sTfR test done?
It is used to evaluate iron deficiency, particularly when ferritin results may be unreliable due to inflammation or chronic disease.
Do I need to fast for this test?
No, fasting is not required for the sTfR serum test.
What sample is needed?
A serum sample is required, typically 2 mL (minimum 1 mL) collected in a serum separation tube (SST).
How should the sample be transported?
The sample should be shipped refrigerated or frozen.
How long does it take to get results?
If the sample reaches the lab by 9 am on Monday or Thursday, the report is available the same day.
What do high levels of sTfR mean?
High levels usually indicate iron deficiency, as the body increases transferrin receptors when iron supply is insufficient.
Can sTfR distinguish between iron deficiency anaemia and anaemia of chronic disease?
Yes, sTfR is valuable for this distinction because it is not affected by inflammation, unlike ferritin.
Are there any interfering factors?
Conditions with increased red blood cell production, such as haemolytic anaemia, may also elevate sTfR. Sample hemolysis can also affect results.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings of the sTfR Serum Test in many cities.
What is the cost of the test?
The price is ?1755 across India.
Who should take this test?
Individuals with symptoms of anaemia such as fatigue, weakness, and paleness, or those with uncertain iron status during chronic disease, may be advised to take this test.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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