TGFB3 Gene Arrhythmogenic right ventricular cardiomyopathy type 1 NGS Genetic Test
Also known as: ARVC1, Arrhythmogenic Right Ventricular Cardiomyopathy Type 1
TGFB3 Gene Arrhythmogenic right ventricular cardiomyopathy type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the TGFB3 Gene NGS Genetic Test is to identify mutations in the TGFB3 gene that cause Arrhythmogenic Right Ventricular Cardiomyopathy Type 1 (ARVC1). This aids in accurate diagnosis, risk stratification, family planning, and tailored treatment strategies to prevent complications such as arrhythmias and sudden cardiac death.
- Test Code
- 2496
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No special preparation required. Ensure proper identification and consent. For blood samples, avoid excessive physical activity prior to collection.
Method: Venipuncture or saliva collection
Laboratory Analysis
Blood draw via venipuncture or saliva collection using a provided kit. Minimal discomfort expected.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities unless advised otherwise.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the TGFB3 Gene NGS Genetic Test is to identify mutations in the TGFB3 gene that cause Arrhythmogenic Right Ventricular Cardiomyopathy Type 1 (ARVC1). This aids in accurate diagnosis, risk stratification, family planning, and tailored treatment strategies to prevent complications such as arrhythmias and sudden cardiac death.
How to Prepare
- Use sterile equipment for blood collection
- For saliva, avoid eating or drinking 30 minutes prior
- Label samples correctly with patient details
- Store at ambient room temperature as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for TGFB3 mutations is crucial for risk assessment, family screening, and personalized management of Arrhythmogenic Right Ventricular Cardiomyopathy Type 1 to prevent sudden cardiac events."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrect labeling or missing documentation
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of ARVC1 due to TGFB3 mutation. Recommend cardiac monitoring, family screening, and management by a cardiologist.
Negative for pathogenic variant
No TGFB3 mutations detected. ARVC1 may still be possible due to other genes or clinical factors; further evaluation needed.
Variant of uncertain significance (VUS)
Genetic change detected but clinical significance unknown. Requires periodic re-evaluation and genetic counseling.
Consult a cardiologist or genetic specialist if you experience symptoms like palpitations, fainting, or chest pain, or if you have a family history of ARVC1. After testing, discuss results with a healthcare provider for appropriate management.
Limitations
- ⚠Test may not detect all genetic variants due to technical limitations
- ⚠Results require interpretation by a genetic counselor or specialist
- ⚠Does not rule out other causes of cardiomyopathy
Risks & Considerations
- ●Minor bruising or discomfort at blood draw site
- ●Emotional impact of genetic results
- ●Risk of false positives or negatives, though rare with NGS
Interfering Factors
- ●Contaminated or degraded DNA samples
- ●Recent blood transfusions may affect results
- ●Technical errors in sample handling or sequencing
Frequently Asked Questions
What is Arrhythmogenic Right Ventricular Cardiomyopathy Type 1 (ARVC1)?
What does the TGFB3 Gene NGS Genetic Test detect?
Who should consider this genetic test?
How is the test performed?
What is the cost of the TGFB3 Gene NGS Genetic Test?
How long does it take to get results?
Is fasting required before the test?
What do positive results mean?
Can this test be used for family screening?
Are there any risks associated with the test?
Is the test covered by insurance?
How accurate is the TGFB3 Gene NGS Genetic Test?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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