The Non-Invasive Prenatal (NIPT) Twins Test
Short Name: NIPT Twins
Also known as: Non-Invasive Prenatal Screening for Twins, cfDNA Screening for Twin Pregnancy
The Non-Invasive Prenatal (NIPT) Twins Test test available at DNA Labs India for ₹13,000. Uses NGS DNA Sequencing on Whole Blood samples. Results in Reports are typically delivered within 8-10 business days after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of the NIPT Twins Test is to screen for the most common chromosomal aneuploidies in twin pregnancies. Early detection allows parents and healthcare providers to prepare for potential medical needs, plan appropriate prenatal care, and make informed decisions about the pregnancy. It also reduces the need for invasive diagnostic procedures, which carry a small risk of miscarriage.
- Test Code
- 6276
- CPT Code
- 81420
- ICD Code
- Z36.89
- Price
- ₹13,000
- Sample Type
- Whole Blood
- Result Time
- Reports are typically delivered within 8-10 business days after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- NGS DNA Sequencing
Sample Collection
No special preparation is required. Fasting is not necessary. Please carry your clinical history and any relevant ultrasound reports.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. The procedure is quick and causes minimal discomfort.
Report Delivery
You can resume normal activities immediately. There are no restrictions after the test.
Timeline: Reports are typically delivered within 8-10 business days after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the NIPT Twins Test is to screen for the most common chromosomal aneuploidies in twin pregnancies. Early detection allows parents and healthcare providers to prepare for potential medical needs, plan appropriate prenatal care, and make informed decisions about the pregnancy. It also reduces the need for invasive diagnostic procedures, which carry a small risk of miscarriage.
How to Prepare
- Inform the lab if you are taking any blood thinners
- Ensure you are at least 10 weeks pregnant
- Provide accurate clinical history and ultrasound dating
- For home collection, keep your ID and prescription ready
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"NIPT in twin pregnancies is a valuable screening tool, but it is not diagnostic. Confirmatory testing (amniocentesis/CVS) is recommended for positive results. The test is most accurate when performed after 10 weeks of gestation and when the pregnancy is not complicated by vanishing twin syndrome."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Incorrect container (e.g., EDTA tube instead of Streck tube)
- Sample received after 48 hours at room temperature
- Insufficient blood volume
- Label mismatch or missing patient information
Understanding Your Results
Low Risk
The probability of trisomy 21, 18, or 13 is very low. No further action is typically needed, but routine prenatal care should continue.
High Risk
The probability of the condition is elevated. Genetic counseling and diagnostic testing (amniocentesis or CVS) are strongly recommended.
Inconclusive
The test could not provide a definitive result, often due to low fetal fraction. A repeat test or alternative screening may be advised.
Consult your obstetrician or genetic counselor if you receive a high-risk result, if the test is inconclusive, or if you have any concerns about your pregnancy. Early consultation can help you understand your options and plan next steps.
Limitations
- ⚠NIPT is a screening test, not diagnostic
- ⚠False positives and false negatives can occur
- ⚠In rare cases, results may be inconclusive due to low fetal fraction
- ⚠Does not detect all genetic disorders (e.g., microdeletions, open neural tube defects)
- ⚠Not recommended for women with certain cancers or autoimmune diseases
Risks & Considerations
- ●No physical risk to mother or babies
- ●Possible anxiety due to false positive results
- ●Inconclusive results may require repeat testing
Interfering Factors
- ●Maternal obesity (BMI > 40) may reduce fetal fraction
- ●Vanishing twin syndrome can affect accuracy
- ●Maternal chromosomal abnormalities (e.g., mosaicism)
- ●Recent blood transfusion or organ transplant
- ●Gestational age less than 10 weeks
- ●Multiple gestation beyond twins (e.g., triplets) – not validated
Compare With Similar Tests
| Test | The Non-Invasive Prenatal (NIPT) Twins Test | First-Trimester Combined Screening | Quadruple Marker Test | Amniocentesis | Chorionic Villus Sampling (CVS) |
|---|---|---|---|---|---|
| Comparison | The Non-Invasive Prenatal (NIPT) Twins Test |
Frequently Asked Questions
What is the NIPT Twins Test?
How is the NIPT Twins Test different from a singleton NIPT?
When should I take the NIPT Twins Test?
Is the NIPT Twins Test safe for my babies?
What does the test cost?
How accurate is the NIPT Twins Test?
What if my result is high risk?
Can the test determine the sex of the babies?
Do I need to fast before the test?
How long does it take to get results?
Is home sample collection available?
What is the sample type required?
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