Skip to main content
DNA Labs India

TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test

Short Name: TLR5 Genetic Test

Also known as: TLR5 Gene Analysis, Legionnaire Disease Susceptibility Test, TLR5 NGS Test

TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 3, 2026

Overview

To identify genetic variations in the TLR5 gene that may increase susceptibility to Legionnaire disease, aiding in risk assessment and personalized healthcare planning.

Test Code
5264
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Genetic counseling is recommended prior to testing.

Method: Venipuncture or Blood drop

Step 2

Laboratory Analysis

A blood sample will be drawn by a trained phlebotomist using sterile equipment.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Keep the area clean.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling is recommended to understand implications and family history.
2
During the Test:Sample is analyzed using next-generation sequencing (NGS) technology for TLR5 gene variations.
3
After the Test:Results are reviewed by a geneticist and reported with interpretation guidance.

About This Test

Who Should Get This Test

To identify genetic variations in the TLR5 gene that may increase susceptibility to Legionnaire disease, aiding in risk assessment and personalized healthcare planning.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection tubes or FTA cards
  • Label samples correctly with patient details
  • Transport samples at recommended temperatures

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test helps identify genetic risk for Legionnaire disease, enabling personalized prevention strategies and early medical intervention."

Last medically reviewed: September 3, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture or Blood drop

Sample Stability

Blood sample stable for 48 hours at 2-8°C
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Incorrect labeling or missing information

Understanding Your Results

Results indicate the presence or absence of genetic variations in the TLR5 gene that may affect susceptibility to Legionnaire disease.
📊

No pathogenic variants detected

Low genetic risk for Legionnaire disease susceptibility based on TLR5 gene analysis.

Action: Continue standard preventive measures; consult a doctor if symptoms arise.

📊

Pathogenic variant detected

Increased genetic risk for Legionnaire disease susceptibility.

Action: Consult a healthcare provider for personalized prevention and monitoring strategies.

⚠️ When to Consult a Doctor:

If you have a family history of Legionnaire disease, experience symptoms like fever and cough, or have a weakened immune system, consult a doctor for evaluation and possible testing.

Limitations

  • ⚠Test only covers the TLR5 gene; other genetic factors may contribute to susceptibility
  • ⚠Does not diagnose active Legionnaire disease; only assesses genetic risk
  • ⚠Results may not predict disease onset with certainty due to environmental factors

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Potential psychological impact from genetic risk information
  • ●Privacy concerns regarding genetic data

Interfering Factors

  • ●Sample contamination
  • ●DNA degradation due to improper storage
  • ●Hemolyzed blood sample

Compare With Similar Tests

TestTLR5 Gene Legionnaire disease, susceptibility to NGS Genetic TestLegionella Urine Antigen TestRespiratory Culture for LegionellaPCR for LegionellaImmunoglobulin Testing
ComparisonTLR5 Gene Legionnaire disease, susceptibility to NGS Genetic TestDetects active infection, not genetic susceptibility.Identifies bacteria in respiratory samples; genetic test assesses risk.Rapid detection of bacterial DNA; genetic test focuses on host susceptibility.Measures immune response; genetic test identifies inherent risk factors.

Frequently Asked Questions

What is the TLR5 gene?
The TLR5 gene encodes a protein that helps the immune system recognize and respond to bacterial infections, including Legionella pneumophila.
How does TLR5 gene variation affect Legionnaire disease risk?
Variations in the TLR5 gene can impair the immune response, making it harder to fight off Legionella bacteria, thus increasing susceptibility to Legionnaire disease.
What is NGS genetic testing?
Next-generation sequencing (NGS) is a advanced technology that analyzes DNA to identify genetic variations, such as those in the TLR5 gene, with high accuracy.
Who should consider this test?
Individuals with a family history of Legionnaire disease, recurrent respiratory infections, weakened immune systems, or exposure to Legionella bacteria should consider this test.
How is the sample collected?
A blood sample is collected via venipuncture, or a drop of blood can be placed on an FTA card. Home collection is available across India.
What is the cost of the test?
The test costs INR 20000, which includes sample collection, processing, and report generation.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home collection available?
Yes, free home sample collection is available for online bookings in numerous cities across India.
What do the results mean?
Results indicate whether pathogenic variants in the TLR5 gene are detected, which may increase genetic risk for Legionnaire disease susceptibility.
Can this test diagnose Legionnaire disease?
No, this test assesses genetic susceptibility, not active infection. Diagnosis of Legionnaire disease requires specific clinical tests like urine antigen or culture.
Is the test covered by insurance?
Coverage depends on your insurance policy. It is not typically covered under government schemes like PMJAY or CGHS; check with your provider.
How accurate is the test?
The test uses NGS technology for high accuracy in detecting TLR5 gene variations, but results should be interpreted in conjunction with clinical evaluation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

FCGR2B Gene Malaria, resistance to NGS Genetic Test

₹20,000

ICAM1 Gene Malaria, cerebral, susceptibility to NGS Genetic Test

₹20,000

ITS Sequencing

₹5,600

IL12RB2 Gene Atypical Mycobacterial infection, IL12RB2 related NGS Genetic Test

₹20,000

Parvovirus B19 Qualitative PCR Test

₹5,000

Respiratory Panel 5 Test

₹4,500
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.