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TNNC1 Gene Cardiomyopathy, dilated type 1Z NGS Genetic Test

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TNNC1 Gene Cardiomyopathy, dilated type 1Z NGS Genetic Test

Short Name: TNNC1 Gene Cardiomyopathy Test

Also known as: TNNC1 Gene Cardiomyopathy, Dilated Cardiomyopathy Type 1Z

TNNC1 Gene Cardiomyopathy, dilated type 1Z NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the TNNC1 gene cardiomyopathy NGS genetic test is to identify mutations in the TNNC1 gene that cause dilated cardiomyopathy type 1Z. This allows for early diagnosis, personalized treatment plans, and family screening to prevent disease progression and manage symptoms effectively.

Test Code
5229
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of family members affected with cardiomyopathy.

Step 2

Laboratory Analysis

Blood sample is collected via venipuncture or using an FTA card for one drop of blood.

Step 3

Report Delivery

Sample is processed for DNA extraction and NGS analysis. Results are available in 3 to 4 weeks.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling. No fasting required.
2
During the Test:Blood sample collection via venipuncture or FTA card.
3
After the Test:Sample sent for NGS analysis. Results delivered in 3 to 4 weeks.

About This Test

Who Should Get This Test

The purpose of the TNNC1 gene cardiomyopathy NGS genetic test is to identify mutations in the TNNC1 gene that cause dilated cardiomyopathy type 1Z. This allows for early diagnosis, personalized treatment plans, and family screening to prevent disease progression and manage symptoms effectively.

How to Prepare

  • Use sterile equipment for blood draw
  • Label samples correctly with patient details
  • Store samples as per lab guidelines

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for TNNC1 gene mutations is crucial for early diagnosis and management of dilated cardiomyopathy, especially in families with a history of heart conditions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Sample Stability

Blood samples stable for 24 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the TNNC1 gene. Positive results confirm genetic predisposition to dilated cardiomyopathy type 1Z, while negative results suggest no known mutations, but clinical evaluation may still be needed.
📊

Positive

Pathogenic variant detected in TNNC1 gene, indicating genetic cardiomyopathy. Consult a cardiologist for management.

📊

Negative

No pathogenic variants detected. Symptoms may be due to other causes; further evaluation recommended.

📊

Variant of Uncertain Significance (VUS)

Genetic variant found but clinical significance unknown. Genetic counseling and follow-up testing advised.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like shortness of breath, fatigue, or irregular heartbeat, or if there is a family history of cardiomyopathy. After testing, discuss results with a genetic counselor or cardiologist for appropriate management.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation and genetic counseling

Risks & Considerations

  • ●Minimal risk from blood draw such as bruising or infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Incorrect sample collection or storage

Frequently Asked Questions

What is TNNC1 gene cardiomyopathy?
TNNC1 gene cardiomyopathy is a type of dilated cardiomyopathy caused by mutations in the TNNC1 gene, leading to weakened heart muscle and impaired pumping.
What are the symptoms of dilated type 1Z cardiomyopathy?
Symptoms include shortness of breath, fatigue, swelling in legs and ankles, irregular heartbeat, dizziness, and difficulty breathing while lying down.
How is TNNC1 gene cardiomyopathy diagnosed?
Diagnosis involves physical exams, ECG, echocardiograms, and genetic testing using NGS to detect TNNC1 gene mutations.
What is NGS genetic testing?
NGS (next-generation sequencing) is a high-throughput DNA sequencing technology that analyzes multiple genes simultaneously to detect mutations.
What is the cost of the TNNC1 gene cardiomyopathy NGS test?
The cost in India is approximately INR 20,000, with home sample collection available.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
How long does it take to get the test results?
Results are typically available in 3 to 4 weeks after sample collection.
What should I do before the test?
Provide clinical history and undergo a genetic counseling session to discuss family history and test implications.
Are there any risks associated with genetic testing?
Risks are minimal, such as bruising from blood draw, but there may be psychological impacts from results.
What does a positive test result mean?
A positive result indicates a pathogenic mutation in the TNNC1 gene, confirming genetic predisposition to cardiomyopathy. Consult a cardiologist for management.
Can this test be used for family screening?
Yes, genetic testing can identify at-risk family members, enabling early monitoring and intervention.
Is the test covered by insurance?
Coverage depends on insurance plans; it is not typically covered under government schemes like PMJAY or CGHS. Check with your provider.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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